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APNASPENAspen Pharmacare Hldgs14474-176 (-1.20%)

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

Financial

Aspen’s half-year revenue increases 13% to R19.8 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), a leading pharmaceutical company in the southern hemisphere, has announced favourable results for the six months ended 31 December 2016. Stephen Saad, Aspen Group Chief Executive said, “The Group has transformed into a global multinational organisation focused on therapeutic specialties over the past few years. This has been a significant undertaking which has required substantial investment in order to build the necessary infrastructure. The contribution from the anaesthesia portfolio acquired from AstraZeneca with effect from 1 September 2016 boosted performance in a period where there were a number of challenges in the operating environment. Particularly pleasing was the marked improvement in cash generated from operating activities which more than doubled as measures to improve working capital management took effect.” GROUP PERFORMANCE • Revenue increased by 13% to R19.8 billion. • Normalised headline earnings per share rose 6% to 692.0 cents. • Normalised EBITDA rose by 7% to R5,5 billion. • Operating cash flow per share escalated 111% to 708,7 cents. • Headline earnings per share increased 53% to 640,9 cents. In addition to the anaesthetics acquisition, the conclusion of a supply and distribution agreement with a major pharmaceutical company which contributed a further R0.4 billion to revenue from the sale of Hydroxyprogesterone Caproate (HPC) in the USA had a positive impact on performance. These upsides were partially offset by the following factors: • The anticipated decline in the South African business which is nonetheless well on its path to recovery; • Margin pressure in the Latin American nutritional business due to reduced production activity as surplus inventories arising from Aspen’s withdrawal from Venezuela were redeployed; • Legislated price decreases, GBP weakness following the Brexit vote, supply constraints and adjustments to the distribution model weighing on performance in the Europe CIS territory; and • Foreign exchange losses, primarily arising from the Rand strengthening against forward exchange contracts. INTERNATIONAL BUSINESS The International business remained the largest segment of the Group, contributing 50% to revenue from customers. Sales to customers in this business increased 11% to R10.0 billion. The Europe CIS territory was the biggest contributor to the International business, increasing sales to customers by 2% to R6.7 billion. Sales of finished dose form pharmaceutical products to healthcare providers (“commercial pharma”) in this territory were up 9% to R4.5 billion. This performance benefitted from the inclusion of the AZ anaesthetics with the offsetting factors mentioned earlier tempering growth achieved. In Latin America, revenue from customers increased 11% to R2.0 billion and commercial pharma sales were 26% higher at R1.3 billion. Excluding the AZ anaesthetics, the underlying pharmaceutical portfolio increased sales 4% to R1.0 billion. Revenue from nutritionals grew in local currencies, but the weakness of the Mexican Peso, in particular, caused reported revenue to decline 9% to R0.7 billion. Margins were unfavorably affected by lower volumes of production in the Vallejo manufacturing site in Mexico for the reasons reported earlier. In the USA, the arrangements with the initially appointed distributor for HPC were terminated and a supply and distribution agreement was signed with a major pharmaceutical company which acquired R0.4 billion of product. Future sales of HPC in the USA will be dependent on the success of this distributor in placing the product in the trade. It is unlikely that there will be further material sales of HPC by Aspen during the 2017 calendar year. Capital projects to enhance production efficiency and ensure highest technical support levels continue at the Notre Dame de Bondeville site in France. At the Oss active pharmaceutical ingredient site in the Netherlands, new capacity is being added and investment in the sustainability of the site is ongoing. SUB-SAHARAN BUSINESS In light of the cancellation of the collaboration with GSK in SSA outside of South Africa, the business segment previously referred to as SSA has been combined with South Africa under the heading of the SSA business. Sales to customers in SSA declined 1% to R4.6 billion. Nutritionals revenue grew 9% to R0.5 billion and manufacturing revenue improved 34% to R0.7 billion. However, as previously communicated, commercial pharma remained under pressure as the resolution of supply chain issues continued, causing sales to decline 8% to R3.4 billion. Despite a month-long strike at the Port Elizabeth and East London manufacturing sites in August, significant progress has been achieved in overcoming the supply constraints affecting the commercial pharma division which delivered improved results in the latter months of the period. The building of a second sterile facility in Port Elizabeth is underway, creating new opportunities to bring additional production to this site. ASIA PACIFIC BUSINESS Sales to customers in the Asia Pacific business increased 36% to R5.2 billion. This region benefits most from the AZ anaesthetics which added R1.6 billion to the sales achieved. In Australasia sales from the base pharmaceutical portfolio grew 3% to R2.3 billion. Sales of nutritionals were 23% lower at R0.4 billion and margin percentages came under pressure. The Australian nutritional industry continues to adapt to lower demand following the withdrawal of informal traders barred from importing product into China. In Asia, the business has expanded substantially with the addition of the AZ anaesthetics. Trade has commenced in China where R0.6 billion of anaesthetic sales was achieved in the period. The underlying commercial pharma portfolio in Asia advanced revenue 17% to R0.9 billion. PROSPECTS In transforming Aspen into a global multinational organisation, it has been necessary to build infrastructure, establish new supply sources and transition management of product portfolios across the world. There have been resultant inefficiencies in overhead structures and working capital management which continue to receive high levels of focus. Unfavourable currency movements and legislated price cuts have also placed pressure on performance. Consequently, this will dilute the synergies realised from various projects. Results in the second half of the 2017 financial year will be influenced by the strengthening of the Rand which, if sustained, will dilute foreign earnings which comprise the greatest portion of Aspen’s income. The outlook to 30 June 2017 will

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Aspen’s comparable revenue increases by 12% to R35.4 billion

Aspen’s comparable revenue increases by 12% to R35.4 billion Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), a leading pharmaceutical company in the southern hemisphere, has announced positive results for the year ended 30 June 2016 notwithstanding economic pressures and currency weaknesses.   Stephen Saad, Aspen Group Chief Executive said, “The positive results underpin the strong foundation set which the business will build on in the 2017 financial year. The recent transactions, with a focus on anaesthetics which has been identified as a key therapeutic category for the Group’s strategic development plans, will further strengthen Aspen’s presence in the hospital sector. The International business remained the largest contributor to Group revenue and delivered strong comparable revenue growth. Manufacturing revenue from South Africa’s Active Pharmaceutical Ingredients (“APIs”) and finished dose forms showed pleasing growth of 52% and 69% respectively. Asia Pacific recorded a 11% comparable revenue increase to R7,4 billion, with Japan leading Asia’s 29% increase in sales. Gross revenue in sub-Saharan Africa increased 18% to R3,3 billion.”   GROUP PERFORMANCE Comparable revenue increased by 12% to R35.4 billion. Comparable normalised operating profit before amortisation, adjusted for specific non-trading items improved by 9% to R9.4 billion. Comparable normalised headline earnings per share rose 15% to 1222 cents. A dividend of 248 cents per ordinary share was declared.   As reported in the interim results, the factors set out below have significantly affected comparability with the results of the prior year and need to be considered when assessing performance for the 2016 financial year: The completion on 31 August 2015 of the divestment of the generics business conducted in Australia as well as certain branded products distributed in Australia to Strides group companies, the related termination of license arrangements in Australia and the completion on 1 October 2015 of the divestment of a portfolio of products distributed in South Africa to Litha Pharma (collectively “the Divestments”). The Divestments gave rise to a pre-tax profit on disposal of R1,6 billion. However, as a consequence of the timing of these transactions, the contribution to the trading results by the Divestments is substantially reduced in the 2016 financial year. In the period from 1 July 2015 until the effective date of divestment, revenue from the Divestments was R0,2 billion whereas revenue from the Divestments for the year ended 30 June 2015 was R1,8 billion.   The economic situation in Venezuela deteriorated over the year to 30 June 2016 and the Venezuelan authorities have increasingly limited authorisations to pay for pharmaceutical imports using the official DIPRO rate during this period of between Venezuelan Bolivar (“VEF”) 6,30 and 10,00 per US Dollar (“USD”). As a consequence of the limited payment approvals and the uncertain economic and political situation in Venezuela, before reporting the interim results for the 6 months ended 31 December 2015 , the Group concluded that it would be more appropriate to apply the DICOM exchange rate (VEF628.34 per USD at 30 June 2016) to report the Venezuelan business’ financial position, results of its operations and cash flows for the year ended 30 June 2016. This has resulted in a one-off currency devaluation loss on foreign denominated liabilities of R870 million.   The profit arising from the Divestments, the currency devaluation loss and the hyperinflationary adjustments relating to Venezuela are excluded, in addition to other specific non-trading items, in determining normalised performance. In order to provide meaningful comparability of the financial performance of the ongoing underlying business, a comparable measure has been determined by removing the contribution from the Divestments and including the results of Aspen’s business in Venezuela translated at VEF628.34 per USD in the prior reporting period.   The key performance measures for the Group for the year ended 30 June 2016 and the percentage change from the prior year are summarized as follows:     Revenue   Operating profit before amortisation   HEPS**   Comparable normalised*** R35,4 billion +12% R9,4 billion* +9% 1 222,0 cents +15% Normalised R35.6 billion -2% R9,5 billion* +3% 1 263,7 cents +10% Unadjusted R35,6 billion -2% R9,6 billion +7% 889.0 cents -23% * operating profit before amortisation, adjusted for specific non-trading items ** headline earnings per share *** The comparable information has been derived from the reviewed financial information and has not been reported on by Aspen’s auditors. This information has been prepared for illustrative purposes only and is the responsibility of the Board of Directors of Aspen   INTERNATIONAL BUSINESS The International Business increased comparable revenue 19% to R18,9 billion and grew comparable operating profit before amortisation, adjusted for specific non-trading items (“EBITA”), 15% to R5,9 billion.   Commercial revenue from pharmaceutical product sales to health care providers in Europe and the Commonwealth of Independent States (“Europe CIS”) improved 22% to R8,5 billion. The acquisition of Mono-Embolex, a thrombolytic product with almost all of its sales in Germany, in the second half of the previous year further strengthened Aspen’s portfolio in this therapeutic area.   In Latin America (excluding Venezuela), revenue to customers increased 3% to R3,5 billion. Nutritional sales were the growth driver, increasing 18% and Infacare was successfully launched in Mexico, securing an important government tender. Aspen has suspended trade in Venezuela pending an improvement in the economic conditions.   Sales to customers in the North America and the Middle East North Africa territories increased strongly off relatively low bases, growing by 42% and 51% respectively.   Manufacturing revenue continued to advance with particularly strong growth in active pharmaceutical ingredient (“API”) sales of 19% to R4,0 billion.   The installation of a new high speed pre-filled syringe filling line at Aspen Notre Dame de Bondeville was completed during the period and commercial production is underway. At Aspen Oss the capital expenditure projects include adding new production capabilities and maintaining the sustainability of the site.   SOUTH AFRICAN BUSINESS Comparable revenue in South Africa was down 1% at R8,1 billion. Nutritionals products maintained their growth momentum, adding 11% to revenue and there were impressive increases in manufacturing revenue for both APIs (+52%)

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Aspen’s profit after tax increases by 35%

Aspen’s profit after tax increases by 35% Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), a leading pharmaceutical manufacturer in the southern hemisphere, has announced pleasing results for the six months ended 31 December 2015. The Group delivered solid growth in a period marked by economic stress and weakening market currencies. The factors set out below have significantly affected the comparability of the results with those of the prior period: The completion on 31 August 2015 of the divestment of the generics business conducted in Australia as well as certain branded products distributed in Australia to Strides group companies, the related termination of license arrangements in Australia and the completion on 1 October 2015 of the divestment of a portfolio of products distributed in South Africa to Litha Pharma (collectively “the Divestments”). The Divestments gave rise to a pre-tax profit on disposal of R1.7 billion. However, as a consequence of the timing of these transactions, the contribution to the trading results by the Divestments is substantially reduced in the current period. In the period from 1 July 2015 until the effective date of divestment, revenue from the Divestments was R202 million whereas revenue from the Divestments for the six months ended 31 December 2014 was R1 148 million. The economic situation in Venezuela deteriorated over the 6 months to December 2015 and the Venezuelan authorities have increasingly limited authorisations to pay for pharmaceutical imports using the official CENCOEX rate during this period of Venezuelan Bolivars (“VEF”) 6.30 per US Dollar (“USD”). As a consequence of the limited payment approvals and the uncertain economic and political situation in Venezuela, the Group has concluded that it would be more appropriate to apply the SIMADI exchange rate of VEF 200 per USD to report the Venezuelan business’ financial position, results of its operations and cash flows for the 6 months ended 31 December 2015. This has resulted in a one-off currency devaluation loss on foreign denominated liabilities of R841million. The profit arising from the Divestments, the currency devaluation loss and the hyperinflationary adjustments relating to Venezuela are excluded in determining normalised headline earnings per share (“NHEPS”) which increased by 14%. In order to provide meaningful comparability of the financial performance of the ongoing underlying business, a measure described as comparable NHEPS has been determined by removing the contribution by the Divestments from NHEPS and including the results of Aspen’s business in Venezuela translated at VEF 200 per USD in the prior reporting period. Comparable NHEPS for the 6 months ended 31 December 2015 was 640,9 cents, an increase of 21%. Applying the same principles, comparable revenue increased by 8% and comparable operating profit increased by 8%. GROUP PERFORMANCE Revenue excluding the effect of the Divestments, increased by 8% to R 17.3 billion. Profit after tax increased 35% to R3.3 billion. Comparable normalised headline earnings per share increased by 21% to 640,9 cents. Normalised headline earnings per share improved by 14% to 655.5 cents. Borrowings, net of cash, increased R3.5 billion over the period to R33.5 billion. Group operating cash flows were negatively affected by a R1.8 billion increase in working capital over the period. Stephen Saad, Aspen Group Chief Executive said, “Performance was led by the International business where the Europe CIS region made a strong contribution. The nutritional products in South Africa and in Asia Pacific also achieved good growth. The completion of the Divestments marks an important step in achieving increased focus in the South African and Asia Pacific businesses. Further meaningful advances in the implementation of Aspen’s strategic objectives have been made and we are seeking to grow the business in targeted therapeutic categories. We remain alert to opportunities to expand our product portfolio in these areas of focus.” INTERNATIONAL BUSINESS The International Business improved revenue 2% to R9.0 billion and raised operating profit before amortisation, adjusted for specific non-trading items (“EBITA”), 16% to R2.8 billion. Revenue was unfavourably affected by R836 million due to the devaluation of the Venezuelan contribution. Excluding the effect of the devaluation, revenue increased 14% in the remainder of the International business. Revenue from customers in Europe and the Commonwealth of Independent States (“Europe CIS”) increased 21% to R6.1 billion. Finished dose form pharmaceutical sales to healthcare providers were up 20% to R4.1 billion. The acquisition of Mono-Embolex, with almost all of its sales in Germany, in the second half of the previous year further strengthened Aspen’s offering in this therapeutic area and added to growth. However, the contribution from Russia fell sharply due to the significant weakening of the Ruble. API sales continued to grow and were the largest part of the balance of the revenue from Europe CIS. Sales to customers in Latin America (excluding Venezuela) declined by 1% to R1.7 billion, unfavourably influenced by difficult socio-economic conditions in Brazil. The nutritionals products in the region maintained their positive growth momentum with revenue rising 12%. Demand for Aspen’s pharmaceutical products was strong, but performance has continued to be suppressed by unreliable supply of certain key products by contract manufacturers. The devalued contribution from Venezuela is no longer material to the Group.| Sales to customers in the Rest of the World increased 4% to R922 million, led by a positive performance in the Middle East North Africa territory. The installation of a new high-speed pre-filled syringe filling line at Aspen Notre Dame de Bondeville (“Aspen NDB”) was completed during the period and commercial production is about to commence. At Aspen Oss capital expenditure projects are ongoing, focused on the sustainability of the site. SOUTH AFRICAN BUSINESS In the South African business revenue was 3% lower at R4.2 billion. Excluding the effect of the Divestments, revenue improved by 4%. The nutritionals products were the leading performer, with revenue growing 15% to R402 million. In the balance of the private sector, branded and generic pharmaceuticals performed satisfactorily. However, supply problems severely undermined the performance of the over-the-counter (“OTC”) products with a consequential decline in key OTC brands. Sales in the public sector (excluding

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Aspen’s revenue increases 22% to R36 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), the sixth largest generic company in the world, has announced excellent results for the year ended 30 June 2015. These results benefitted from the contribution of acquisitions concluded during the prior year. GROUP PERFORMANCE Revenue increased by 22% to R36.1 billion. Operating profit rose by 14% to R8.4 billion. Normalised headline earnings, being headline earnings adjusted for specific non-trading items, increased by 15% to R5.6 billion. Normalised headline earnings per share improved by 15% to 1 219 cents. Borrowings, net of cash, increased R0.2 billion to R30.0 billion. R2.5 billion of this arose from unfavourable relative foreign exchange rate movements. Group operating cash flows remained strong and cash generated from operating activities increased by 26% to R4.8 billion. A capital distribution of 216 cents per ordinary share was declared. Stephen Saad, Aspen Group Chief Executive said, “The excellent results were led by the International business which remained the largest contributor to the Group, delivering 49% of gross revenue. Sales in Asia jumped 39% to R1.3 billion due to a combination of organic growth and recent acquisitions led by strong advances in Japan. The results were achieved despite an unfavourable exchange rate environment affecting the Group’s principal trading currencies, particularly relative to the US Dollar, which resulted in a devaluing of revenue flows and an increase in cost of goods. INTERNATIONAL BUSINESS In the International business, revenue climbed 46% to R18.6 billion and operating profit before amortisation, adjusted for specific non-trading items (“EBITA”), advanced 42% to R5.2 billion. The International business performance was assisted by the inclusion of the significant transactions completed during the prior year and contributed more than half of Group EBITA.  The disposal of the rights to commercialise the fondaparinux products (being Arixtra and the authorised generic thereof) in the United States to Mylan, for a consideration of USD 300 million, became effective during the first half of the 2015 financial year with the consequential loss of contribution. Revenue from customers in Europe and the Commonwealth of Independent States (“Europe CIS”) increased 45% to R10.5 billion.  Finished dose form pharmaceutical sales to healthcare providers comprised R6.9 billion of the total sales.  The acquisition in the second half of the year of Mono-Embolex, an anti-coagulant with almost all of its sales in Germany, further strengthened Aspen’s offering in this therapeutic area.  The largest part of the balance of the sales in the region was from active pharmaceutical ingredient (“API”) sales.  Relative weakness of the Europe CIS currencies to the Rand reduced reported revenue from this region. Sales to customers in Latin America (excluding Venezuela) grew 44% to R3.4 billion, supported by the infant nutritionals acquisition in the prior year.  Performance was constrained due to poor supply by contract manufacturers of certain key pharmaceutical products.  In Venezuela, sales to customers were up 143% to R2.7 billion.   The results in Venezuela have been influenced by the application of hyper inflationary accounting principles and a change in the rate of exchange applied in the translation of local currency results from the prior year. The net effect of these entries on EBITA is not significant. Sales to customers in the Rest of the World were down 10% to R1.6 billion, influenced by the disposal of the fondaparinux products for the United States to Mylan. Capital expenditure projects remain underway in the Netherlands at Aspen Oss (Netherlands) and in France at Aspen Notre Dame de Bondeville (“Aspen NDB”).  At Aspen Oss, the projects are focused on the repurposing of facilities and at Aspen NDB, the addition of a new pre-filled syringe filling line is well advanced. SOUTH AFRICAN BUSINESS Revenue in the South African business increased by 16% to R8.6 billion.  Private sector pharmaceutical sales improved 12% through a combination of organic growth and new product launches.  Public sector sales grew 14% led by demand under the antiretroviral (“ARV”) tender.  The consumer division raised revenue by 23% due to a strong performance from infant nutritionals, with Infacare making impressive gains in its share of this category.   Revenue from manufacturing for third parties also showed a good increase. The increase in the ARV tender revenue coupled with the ongoing weakening of the Rand relative to the US Dollar and high wage and energy cost inflation has placed pressure on EBITA margins. Expansion projects continued at the Port Elizabeth finished dosage form manufacturing site and at the API manufacturing site in Cape Town (“Fine Chemicals”).  In Port Elizabeth, the building of the high containment facility is nearing completion and manufacturing trials in the hormonal suite have commenced.  The packing facility upgrade is complete.  Construction of the additional specialist sterile manufacturing facility has commenced.  At Fine Chemicals, production is underway in certain of the newly constructed suites, while other parts of this expansion and upgrade project remain in progress. ASIA PACIFIC BUSINESS Revenue in the Asia Pacific business was 5% lower at R8.1 billion and EBITA declined by 10% to R1.7 billion.  In Australasia sales to customers were 8% lower at R7.2 billion.  The key focus areas of branded pharmaceuticals and infant nutritionals both showed positive growth.  This was, however, reversed by the effect of disposals as well as the termination of licenses and contract manufacturing arrangements in the second half of the prior financial year.  These were undertaken in accordance with the strategy to achieve greater focus in this business.  Cost of goods in Australia increased due to the weakening of the Australian Dollar against the US Dollar in which many input costs are denominated. Sales to customers in Asia accelerated by 39% to R1.3 billion through a combination of organic growth and recent acquisitions, led by strong advances in Japan. SUB-SAHARAN BUSINESS In Sub-Saharan Africa, revenue was 1% higher at R2.8 billion.  A disappointing performance from the GSK Aspen Healthcare for Africa Collaboration, which was hampered by supply problems, limited performance in the region.  Weakening in-market currencies contributed to narrowing margins and a reduction of 6% in EBITA to R313 million. PROSPECTS Strategically, the

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Aspen’s half-year gross revenue surges by 47% to R19 billion

Aspen’s half-year gross revenue surges by 47% to R19 billion Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), the fifth largest generic company in the world, has announced stellar results for the six months ended 31 December 2014, which have primarily been driven by its offshore businesses. GROUP PERFORMANCE Gross revenue increased by 47% to R19.0 billion. Operating profit rose by 50% to R4.3 billion. Net profit after tax and earnings per share each advanced 27% to R2.5 billion and 539 cents respectively. Normalised headline earnings, being headline earnings adjusted for specific non-trading items, increased by 22% to R2.6 billion. Normalised headline earnings per share improved by 22% to 569 cents. Borrowings net of cash reduced by R1.2 billion while cash generated from operating activities accelerated 128%. Stephen Saad, Aspen Group Chief Executive said, “We are pleased with the Group’s excellent performance. These results were underpinned by the expansion of our International business, which now contributes 46% to the Group’s gross revenue. The Nutritionals products have also made an increased contribution to the Group..” “The global pharmaceutical industry is experiencing a prevalence of restructuring and consolidation, which creates acquisitive opportunities. Aspen is well placed to participate in these and its proven capability to successfully execute complex multi-territory transactions makes Aspen a strong candidate for such opportunities,” said Saad INTERNATIONAL BUSINESS Revenue in the International business was 158% higher at R8.8 billion and performance was boosted by the inclusion of the significant transactions completed during the previous financial year. Revenue from the Europe CIS business climbed 229% to R5.1 billion from finished dose form pharmaceuticals and active pharmaceutical ingredient sales. Revenue in Latin America advanced 118% to R2.6 billion, largely driven by the recent infant milk formula acquisition, while sales to customers in the Rest of the World were up 36% to R0.9 billion. Capital expenditure projects are continuing at Aspen Oss in the Netherlands and at the French-based Aspen Notre Dame de Bondeville site. ASIA PACIFIC BUSINESS Revenue in the Asia Pacific region was 3% higher at R4.4 billion where the Nutritionals products led the way with strong double-digit growth. Sales to customers in Asia continued on an impressive growth trajectory, doubling to R0.6 billion.  SOUTH AFRICAN BUSINESS As the ongoing leading pharmaceutical manufacturer in the country, revenue in the South African business grew by 12% to R4.3 billion. Private sector pharmaceutical sales increased 10% through a combination of organic growth and new product launches. Sales in the public sector were flat. The consumer division raised revenue by 30%, led by the Nutritionals products with Infacare achieving an increase in its share of this category. The capital expenditure projects at the Port Elizabeth finished dose form manufacturing site and the Cape Town API manufacturing site are progressing well. SUB-SAHARAN BUSINESS In Sub-Saharan Africa, revenue improved by 5% to R1.5 billion. Margin improvement initiatives yielded positive results and lifted EBITA 12% to R210 million.     Issued by:         Shauneen Beukes, Shauneen Beukes Communications Tel: +27 (012) 661-8467 : Cell: +27 82 389 8900   Disclaimer We may make statements that are not historical facts and relate to analyses and other information based on forecasts of future results and estimates of amounts not yet determinable. These are forward looking statements as defined in the U.S. Private Securities Litigation Reform Act of 1995. Words such as “believe”, “anticipate”, “expect”, “intend”, “seek”, “will”, “plan”, “indicate, “could”, “may”, “endeavor”, “prospects” and “project” and similar expressions are intended to identify such forward looking statements, but are not the exclusive means of identifying such statements. By their very nature, forward looking statements involve inherent risks and uncertainties, both general and specific, and there are risks that predictions, forecasts, projections and other forward looking statements will not be achieved. If one or more of these risks materialize, or should underlying assumptions prove incorrect, actual results may be very different from those anticipated. The factors that could cause our actual results to differ materially from the plans, objectives, expectations, estimates and intentions expressed in such forward looking statements are discussed in each year’s annual report. Forward looking statements apply only as of the date on which they are made, and we do not undertake other than in terms of the Listings Requirements of the JSE Limited, any obligation to update or revise any of them, whether as a result of new information, future events or otherwise. All profit forecasts published in this report are unaudited.

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Aspen’s revenue soars by 53% to R29.5 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), the fifth largest generic company in the world and Africa’s largest pharmaceutical manufacturer, has announced excellent results for the year ended 30 June 2014. GROUP PERFORMANCE Revenue increased by 53% to R29.5 billion. Operating profit rose by 47% to R7.4 billion. Normalised headline earnings, being headline earnings adjusted for specific non-trading items, was up 27% to R4.9 billion. Normalised headline earnings per share advanced 27% to 1064 cents. A capital distribution of 188 cents per ordinary share was declared by way of a capital reduction payable out of contributed tax capital to shareholders. Stephen Saad, Aspen Group Chief Executive said, “The Board is pleased with the Group’s performance, particularly that of the International business which was the most significant growth driver and the largest business segment contributor to revenue and to operating profit.  Accelerated revenue from Latin America bodes well for that region while Asia remains an important growth territory. The South African business continues to retain its position as the leading pharmaceutical company in the private and public sectors of this market, and Sub-Saharan Africa also delivered a pleasing performance.” SIGNIFICANT TRANSACTIONS A number of significant transactions were completed during the financial year and were influential in the performance of the Group.  These transactions have created important new opportunities for Aspen in both product offering and geographic coverage.  The key terms of these transactions are set out below: The acquisition of the active pharmaceutical ingredient (“API”) manufacturing business, primarily in the Netherlands, from MSD for EUR 31 million net of cash acquired, became effective 1 October 2013 and trades as Aspen Oss and Aspen API. The acquisition of a portfolio of 11 branded finished dose form molecules from MSD in a related transaction for USD 600 million, of which USD 67 million is subject to delayed payment terms, became effective on 31 December 2013. The acquisition of the Arixtra and Fraxiparine/Fraxodi thrombolytic brands worldwide (excluding China, India and Pakistan) from GlaxoSmithKline (“GSK”) for GBP 505 million became effective on 31 December 2013. In a connected transaction which became effective on 30 April 2014, a further GBP 194 million was paid to GSK for the acquisition of the specialised sterile production site in France which manufactures these brands and the related inventory. This business trades as Aspen Notre Dame de Bondeville (“Aspen NDB”). The acquisition from Nestlé of certain licence rights to infant nutritional intellectual property, net assets, including a production facility in Mexico, and shares in infant nutritional businesses in several countries in Latin America for a purchase consideration of USD180 million was completed with effect from 28 October 2013. The acquisition from Nestlé of certain rights to intellectual property licenses and net assets of the infant nutritionals business previously conducted by Pfizer in certain southern African territories, including South Africa, was approved by the competition authorities and became effective on 27 January 2014. The purchase consideration for this transaction of USD 43 million was prepaid in the prior financial year. INTERNATIONAL BUSINESS The International business advanced revenue 242% to R12.7 billion and increased operating profit before amortisation, adjusted for specific non-trading items (“EBITA”), 144% to R3.6 billion.  The margin percentage in the International business narrowed as a consequence of lower margin rates in the Aspen Oss business and in the infant nutritional business in Latin America acquired during the year.  The International business gained most from the significant transactions completed during the financial year and contributed 40% of Group gross revenue and 47% of Group EBITA.  Performance was also boosted by organic growth from the pre-existing global brands portfolio. With effect from 1 January 2014 Aspen introduced a specialised sales and marketing team into Europe and the Commonwealth of Independent States (formerly the Soviet Union) (“CIS”) for the first time. Aspen now has a substantial footprint across Europe and the CIS with more than 400 active sales and marketing focused personnel in 18 countries, the majority of whom transferred from GSK in terms of the arrangements under the acquisition of Arixtra and Fraxiparine. Revenue from customers in Europe CIS was over 5 times greater than the prior year at R7.2 billion.  Of this amount, R4.0 billion was derived from sales of finished dose form pharmaceuticals to healthcare providers and the major portion of the balance was from sales of APIs. There was also a strong acceleration of revenue from customers in Latin America where sales climbed 122% to R3.5 billion.  The acquisitions made by the Group accounted for the largest portion of this increase despite some supply issues, supported by good performances in Mexico and Venezuela. In the Rest of the World, sales to customers were up 181% to R1.7 billion influenced by an increased exposure to the US resulting from the acquisitions concluded during the year and by positive progress in the Middle East North Africa territory. Significant activity has been undertaken at the Aspen Oss API manufacturing site and also at the Aspen NDB specialist sterile manufacturing site.  At both of these sites it has been necessary to disentangle the manufacturing operations from the systems of the vendors.  Capital expenditure projects are also ongoing at both these sites.  At Aspen Oss, improvements to the safety profile of the site are receiving urgent attention and at Aspen NDB, additional capacity is being added with the construction of an entirely new production area. On 10 September 2014, Aspen Global Incorporated (“AGI”) entered into an agreement with Mylan Ireland Limited (“Mylan”) in terms of which AGI will dispose of its rights to commercialise the fondaparinux products it recently acquired from GSK (being Arixtra and the authorised generic thereof) in the United States (“US”) to Mylan. AGI will also enter into a supply agreement to supply these fondaparinux products to Mylan on specified terms.  The transaction will complete upon the satisfaction of certain conditions precedent, including regulatory approvals.  Mylan will pay Aspen USD 225 million upon completion of the transaction. An additional USD 75 million will be held in escrow and

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Aspen’s half-year revenue increases to R12 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), the ninth largest generic company in the world and Africa’s largest pharmaceutical manufacturer, has announced excellent results for the six months ended 31 December 2013. Group Performance Revenue increased by 33% to R12.0 billion. Operating profit improved by 16% to R2.9 billion after absorbing transaction costs of R143 million relating to the significant new business acquisitions undertaken in the reporting period. Normalised headline earnings, being headline earnings adjusted for specific non-trading items, rose 23% to R2.1 billion. Normalised diluted headline earnings per share increased by 23% to 467.4 cents. Stephen Saad, Aspen Group Chief Executive said, “The business delivered pleasing returns with the International business leading the Group’s growth with significant advances in revenue and profits through a combination of organic growth and the contribution of completed acquisitions. This momentum is expected to continue as Aspen further extends its emerging market presence to the Commonwealth of Independent States (“CIS”) comprising Russia and the former Soviet Republics, to Central and Eastern Europe (“CEE”) as well as adding to its existing business in Asia and Latin America.” RECENT TRANSACTIONS Aspen has recently undertaken extensive corporate activity which will transform the Group. The following is the status of the material transactions involved: The acquisition of the Active Pharmaceutical Ingredient (“API”) manufacturing business, primarily in the Netherlands, from MSD for EUR31 million plus the value of inventory, became effective on 1 October 2013. The acquisition of a portfolio of 11 branded finished dose form molecules from MSD in a related transaction for USD600 million, of which USD67 million has delayed payment terms, became effective on 31 December 2013. The acquisition of the Arixtra and Fraxiparine/Fraxodi brands worldwide (excluding China, India and Pakistan) from GSK for GBP505 million became effective on 31 December 2013. In a related transaction, a further GBP100 million and EUR113 million has been paid into escrow in respect of the acquisition of the specialised sterile production site in France which manufactures these brands and the related inventory. This transaction is scheduled to become effective on 30 April 2014. The acquisition of certain licence rights to infant nutritional intellectual property, net assets, including a production facility in Mexico, and shares in infant nutritional businesses in several countries in Latin America from Nestlé for a purchase consideration of USD180 million was completed with effect from 28 October 2013. The acquisition from Nestlé of certain rights to intellectual property licenses and net assets of the infant nutritionals business presently conducted by Pfizer in certain southern African territories, including South Africa, has been approved by the competition authorities and became effective on 27 January 2014. SOUTH AFRICAN BUSINESS In the South African business, revenue improved by 8% to R3.8 billion and operating profit before amortisation, adjusted for specific non-trading items (“EBITA”) was unchanged at almost R1.0 billion. Revenue in the Pharmaceutical division advanced 7% to R3.2 billion. In the private sector, double digit percentage growth in revenue was delivered through a combination of solid organic growth and the contribution from new product launches. Aspen grew ahead of the market in all segments of the private sector. In the public sector, significantly reduced prices for antiretrovirals (“ARVs”) and a reduced share of the ARV tender gave rise to revenue contraction which limited the overall performance of the Pharmaceutical division. The decrease in ARV prices, the continued weakening of the Rand and rising inflation in administered costs caused a reduction in margin percentages despite gains achieved in production efficiency and procurement. The Consumer division raised revenue by 14% which was a positive outcome given the economic pressures at play in the retail sector. The Group continued to invest in capital expansion projects to enhance production capacities and capabilities in South Africa. The two major projects underway are the extension of production facilities at Fine Chemicals Corporation in Cape Town which will allow this site to contribute meaningfully to Aspen’s expanded API activities, and the building of the high containment suite in Port Elizabeth which will further strengthen the Group’s strategic manufacturing capabilities. ASIA PACIFIC BUSINESS The region’s record of unbroken growth since inception in 2001 was extended with a rise of 27% in revenue to R4.3 billion supported by products added as a consequence of acquisitions by the Group in the previous financial year. EBITA was up by 4% to almost R1.0 billion as most of the products added to the portfolio were at the lower margins available for distribution services and the ongoing mandated price cuts in Australia weighed on profits. The margin percentage contraction was cushioned by savings achieved in the cost of goods and through a reduction in rebates paid. In Asia, Aspen’s newly established businesses in the Philippines, Malaysia and Taiwan made impressive advances albeit off a low base. Sales to customers in Asian countries increased by 22% to R311 million. INTERNATIONAL BUSINESS The International business led growth in the Group with revenue increasing 94% to R3.4 billion and EBITA rising 79% to R1.1 billion. The acquisition of the API business from MSD effective 1 October 2013 and the completion of the infant nutritional transaction with Nestlé effective 28 October 2013 together added R1.3 billion to revenue at low margins, boosting the sales growth and lowering overall margin percentages. These deals were also influencing factors in the rise in sales to customers in the Latin American (up 60% to R1.2 billion) and Rest of World (up 147% to R2.2 billion) territories. The global brands portfolio was an important driver of the growth achieved in the International business and the margin improvement projects for these products continued to yield favourable outcomes. Contributions from certain territories in this business have also benefitted from relative currency strength against the Rand. SUB SAHARAN AFRICA BUSINESS In Sub Saharan Africa gross revenue advanced by 41% to R1.4 billion while EBITA climbed 53% to R0.2 billion as the good momentum achieved in the second half of the prior year was maintained. PROSPECTS The completion of the recent transactions

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Aspen’s revenue soars to R19.3 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), the ninth largest generic company in the world and Africa’s largest pharmaceutical manufacturer, has announced excellent results for the year ended 30 June 2013. Group Performance Revenue from continuing operations increased by 27% to R19.3 billion. Operating profit from continuing operations rose by 28% to R5 billion. Normalised headline earnings, being headline earnings adjusted for specific non-trading items, advanced 32% to R3.8 billion. Normalised diluted headline earnings per share from continuing operations increased by 31% to 836 cents. Total distribution of 157 cents per share comprising a cash dividend of 131 cents per ordinary share and a capital distribution of 26 cents per ordinary share. Stephen Saad, Aspen Group Chief Executive said, “While all business segments recorded substantial growth, the International business excelled with a superb performance driven by a combination of organic and acquisitive revenue growth.. The largest revenue contribution to the Group came from the Asia Pacific business while Latin America was the fastest growing customer geography.” South African Business In the South African business, revenue improved by 20% to R7.4 billion and operating profit before amortisation, adjusted for specific non-trading items (“EBITA”) increased 11% to R2.0 billion. Revenue in the Pharmaceutical division rose 20% to R6.2 billion driven by organic growth and a strong contribution from new product launches in the private sector. In the public sector expanding demand for antiretrovirals (“ARVs”) added to the growth momentum although the greater weighting of revenue from low margin ARVs was the largest factor in the contraction of margin percentages. The weakening of the rand and rising inflation in administered costs also put pressure on margins although this was partially relieved by gains in production efficiency and procurement savings. The Consumer division delivered an 18% increase in revenue with nutritionals being the biggest growth driver. Innovative new products, growing-up-milk and ready-to-feed infant milk were launched expanding Aspen’s offering in the nutritional sector. Capital expansion projects have continued according to plan at all of the South African sites. In Port Elizabeth, land was acquired immediately adjacent to Aspen’s site. Part of this land is already under construction with the commencement of the building of the high containment suite while the remaining land remains available for future projects. The upgrade of packing capabilities is also underway in Port Elizabeth. The expansion and enhancement of manufacturing capabilities is continuing at Fine Chemicals in line with the strategy to achieve greater vertical integration of this site with Group active pharmaceutical ingredient (“API”) demands. The projects underway in East London and at Clayville are nearing completion. Asia Pacific Business The region’s continuous record of growth since the business was established in this territory in 2001 continued with a gain of 26% in revenue to R7.6 billion and with EBITA increasing by 30% to R1.9 billion. Rand-denominated performance was enhanced by the relative strengthening of the local currencies. The Asia Pacific region was the largest contributor to revenue in the Group for the first time, accounting for 37% of total gross revenue. This was achieved despite the mandated price cuts in Australia imposed by existing legislation. Revenue growth was supported by acquired products and pleasing progress in the Asian territories. EBITA advances benefitted from the continuation of the project to source more competitive product costs including the migration of production to the Port Elizabeth site in South Africa. The newly established subsidiary in Malaysia commenced trade in July 2013 and a further subsidiary has been established in Taiwan. Distribution in Australia of the classic brands portfolio acquired by the Group from GlaxoSmithKline (“GSK”) in December 2012 and the infant milk products acquired by the Group from Nestlé in May 2013 have been successfully taken on. International Business The International business showed strong growth with revenue increasing 48% to R3.7 billion and EBITA rising 59% to R1.5 billion. Latin America showed the biggest advance where sales to customers in this territory climbed 53% to R1.6 billion. A combination of organic and acquisitive growth propelled the Latin American performance despite the impact of the currency devaluation in Venezuela. The global brands portfolio was an important contributor to the growth achieved in the International business and the margin improvement projects for these products continued to yield favourable outcomes. Contributions from certain territories in this business have also benefitted from relative currency strength against the rand. Sub-Saharan Africa Business Gross revenue in Sub Saharan Africa increased 26% to R2.1 billion driven by expanded promotional support. The negative growth in EBITA during the first six months was reversed with an increase of 16% in EBITA in the second six months bringing the result for the year to R252 million, an increase of 2%. Impending Transactions Aspen has undertaken extensive corporate activity over the past year and the following transactions are being progression by Group companies: The acquisition of an API manufacturing business, primarily in the Netherlands, from MSD for approximately €36 million plus the value of inventory, to be effective 1 October 2013. Further details appear in the SENS announcement of 27 June 2013. In a related agreement with MSD, Aspen has an option to acquire a portfolio of 11 branded finished dose form molecules covering a diverse range of therapeutic areas for approximately US$600 million. The most likely date for the acquisition of this portfolio through the exercise of the option is 31 December 2013. Further details appear in the SENS announcement of 27 June 2013. A binding, irrevocable offer submitted to GSK to acquire the Arixtra and Fraxiparine/Fraxodi brands worldwide (excluding China, India and Pakistan) together with the specialised sterile production site which manufactures these brands for approximately £700 million. In terms of the offer, the date of acquisition of the brands would be 31 December 2013 and the date of acquisition of the site would be 30 April 2014. Further details appear in the SENS announcements of 18 June 2013 and 24 July 2013. The acquisition of certain licence rights to infant nutritional intellectual property, net assets

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Media Enquiries

Shauneen Beukes
Group Communications Consultant
+27 31 580 8600
+27 82 389 8900
sbeukes@aspenpharma.com

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