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APNASPENAspen Pharmacare Hldgs13942-103 (-0.73%)

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

Aspen’s revenue increases by 80 percent as international business expands

Johannesburg – JSE listed Aspen Pharmacare Holdings Limited, Africa’s largest pharmaceutical manufacturer, has produced excellent results for the year ended 30 June 2009. Prevailing global economic conditions did little to deter the strength of the Group’s performance, with the South African and Australian businesses continuing to perform well. Aspen’s international expansions resulted in substantially increased contributions from the offshore businesses, delivering an operating profit of R1.076 billion. GROUP PERFORMANCE: Group revenue increased by 80% to R8,450 billion (R4.881 billion). Group operating profit improved by 82% to R2,183 billion (R1.298 billion). Group headline earnings per share (HEPS) grew by 68% to 389.4 cents (231.3 cents). Stephen Saad, Aspen Group Chief Executive said, “The Group’s international operations delivered positive results, delivering an increased contribution to earnings of 47% up from 15% last year. The South African business has achieved excellent growth and has increased its contribution to earnings by 14%, while retaining its position as the market leader in the pharmaceutical sector and improving its market share in all market segments. SOUTH AFRICAN OPERATIONS RETAIN MARKET LEADERSHIP Aspen’s South African business remains the market leader in the total private pharmaceutical market, the private generic market, the public sector pharmaceutical market and in the supply of anti-retrovirals (ARVs) to both the private and the public sectors. Campbell Belman’s independent Confidence Standing Survey of 42 over-the-counter (OTC) companies by 146 top retail pharmacies, again ranked Aspen as the top OTC company for the fourth time in the past six years. The South African business increased revenue by 30% to R4,868 billion amidst difficult trading conditions. Notwithstanding margin pressure, EBITA grew by R149 million to R1,208 billion. Restrictive factors such as accelerated raw material prices, production inflation and legislated fixed Single Exit Prices (SEP) impacted returns in the first half. A margin improvement was seen in the final quarter as a consequence of the Department of Health’s 13.2% increase in SEP in February 2009 and the implementation of the state tender price adjustment mechanism. An impressive performance was delivered by the pharmaceutical division, with revenue increasing by 34% to R3,767 billion. These results were driven by organic volume growth and the successful launches of Truvada, Viread, Vectoryl and Aspen Efavirenz. The consumer division’s 16% revenue increase to R1.101 billion was positive given the depressed retail sector. Leading brands such as Lennon Dutch Medicines, Infacare, S26, Guronsan C and Hamburg Tea delivered a credible performance. Prospects for the ophthalmic portfolio were enhanced with the addition of Eye-gene and Murine, while Melegi, a new infant milk formulation was launched and exported into selected African countries. Additional oral solid dose (OSD) manufacturing capacity was realised in Port Elizabeth with the completion of more packing lines. This provided relief to production pressure driven by unprecedented public sector demand. The new OSD tabletting production plant, presently undergoing validation, will provide further capacity before the end of 2009. The Sterile Facility’s eye-drop suite has commenced exporting Clear Eyes and Murine to Prestige Brands in the United States, while trials have been initiated in the hormonal suite. An explosion in the drying tower at Aspen’s Nutritionals Facility on 18 August 2009 caused extensive damage to that section of the production site. Blending and packing areas were unaffected and production in the drying tower should recommence before the end of the 2010 financial year. Contingency plans have been implemented to ensure continued supply of infant milk formulations to the market. INTERNATIONAL OPERATIONS DELIVER PLEASING RETURNS Over the past 18 months, the Group’s international expansion has been driven by acquisitions in Brazil, Mexico, Venezuela, Tanzania, Kenya and Uganda. With effect from 30 June 2008, the Group’s intellectual property portfolio in international markets was significantly enhanced by the acquisition of four globally branded products, Eltroxin, Lanoxin, Imuran and Zyloric from GSK for GBP 170 million. The global product range was also supplemented by two licensing transactions for branded products with US-based Iroko Pharmaceuticals. Aspen products are now distributed to more than 100 countries across the world. This expansion has resulted in a substantial increase in the contribution from international operations to the Group. Revenue of R3,869 billion was achieved, up from R1,123 billion and EBITA from continuing operations was R1,071 billion, up from R209 million. The global brands comprised R1.438 billion of revenue. Transition of distribution arrangements for the global brands to the Aspen network has already commenced, with the remainder of the transition scheduled in the 2010 financial year. Aspen Australia’s positive performance yielded a 29% increase in revenue to R915 million, despite legislated price cuts. These results were driven by effective product promotions and expanded product offerings. Aspen’s Latin American business recorded revenue of R841 million, but the potential of this territory remains to be realised. Initiatives receiving active attention include the strengthening of management, increasing representation in the private sector, launching new products and establishing a medium-term product pipeline. The Group’s East African business reported revenue of R373 million in a year in which political unrest in Kenya had a negative impact upon trade. Aspen disposed of its 50% shareholding in the ARV active pharmaceutical ingredient manufacturer, Astrix, for USD 39 million, with effect from 31 May 2009. GSK TRANSACTIONS On 12 May 2009 Aspen announced that it had agreed terms on a series of strategic interdependent transactions (“the GSK transactions”) with GSK, being: the acquisition of the rights to distribute GSK’s pharmaceutical products in South Africa; the formation of a collaboration arrangement between Aspen and GSK in relation to the marketing and selling of prescription pharmaceuticals in sub-Saharan Africa; the acquisition by Aspen Global of eight specialist branded products (Alkeran, Leukeran, Purinethol, Kemadrin, Lanvis, Myleran, Septrin and Trandate) for worldwide distribution; the acquisition of GSK’s manufacturing facility in Bad Oldesloe, Germany; and Aspen to issue 68.5 million shares to GSK as consideration for the transactions. The completion of the transactions was subject to the fulfillment of a number of conditions precedent. Certain of these conditions precedent have now been fulfilled, amongst these the approval of the South African Competition Authorities… Continue reading Aspen’s revenue increases by 80 percent as international business expands

Aspen’s S26 Assurance of Quality

A message from Aspen Group Chief Executive, Stephen Saad, to the mothers of South Africa’s babies: “At Aspen we understand that the wellbeing of your baby is of utmost importance. I confidently give you my assurance that Aspen’s S26 infant milk formula available to you in South Africa is of the highest quality. My confidence is based on these facts: Each batch of S26 undergoes as many as 60 different tests, there by ensuring their quality prior to dispatch S26 complies with international quality standards S26 is manufactured in an internationally approved factory S26 has been used by the South African Department of Health S26 has been supplied to South African mothers for 40 years. You can feed your baby with S26 in the sure knowledge that the product is of the highest quality. I have and I would.” The Tanzanian Health authorities recently withdrew S26-1 from the market in that country following four complaints regarding the quality of the product. There have been reports of counterfeit S26 in the Tanzanian market. Quality deterioration may also be caused by non-adherence to required storage conditions. Aspen is actively investigating the matter and will take all measures required to ensure the matter is managed.

Quality of S-26 in South Africa Guaranteed

Johannesburg: Aspen Nutritionals, manufacturer of S-26 and other infant milk formulations (IMFs), confirms that all IMFs manufactured and marketed by Aspen Nutritionals are safe for infant consumption. This statement is being issued in response to a media report concerning the Tanzanian Food and Drug Administration’s withdrawal notification of a consignment of S-26, which, until proven otherwise, could be counterfeit product. Karyn Purchase, Aspen Nutritionals Factory Manager said, “S-26 has been manufactured in South Africa for the past 40 years without any adverse incident being recorded. S-26 and all other IMFs sold by Aspen on the South African market are tested to the highest international standards, meeting not only the latest South African Foodstuffs, Cosmetics and Disinfectants Act and regulations (ACT 54: 1972), but also CODEX / WHO standards applicable to IMFs and Follow-On formulations, FDA CFR21 (applicable legislation “Infant Formula Quality Control Procedures). Aspen’s IMFs have always met all International Quality and Food Safety requirements”. Aspen’s Clayville Facility, which manufactures IMFs, is GMP and HACCP certified through the Perishable Products Export Control Board (PPECB), which is accredited with the South African National Accreditation System (SANAS). Up to sixty individual tests including physical, sensorial, chemical and microbiological testing is performed on every single batch number of IMFs sold by Aspen to ensure that the food safety of our customers is protected 100%. Additionally a complete stability programme is in place to ensure continued suitability and safety, and efficacy of all IMF products up to the shelf life of each product. Independent complete testing of all IMFs to monitor proficiency of local quality control operations is routinely conducted. Testing includes contaminants and residues testing including Melamine and Radionuclides to comply with all local and International guidelines. Issued by: Shauneen Beukes, Shauneen Beukes Communications On Behalf Of: Karyn Purchase, Aspen Nutritionals Factory Manager Tel: (011) 206-9510 : Cell: 083 625 0810

Official statement regarding the alleged purchase transactions entered into between Aspen and Frankel Chemicals

OFFICIAL STATEMENT REGARDING THE ALLEGED PURCHASE TRANSACTIONS ENTERED INTO BETWEEN ASPEN AND FRANKEL CHEMICALS FOR THE PURCHASE BY ASPEN FROM FRANKEL CHEMICALS OF RAW MATERIALS FOR THE MANUFACTURE OF ANTI-RETROVIALS. ASPEN PHARMACARE HOLDINGS LIMITED AND ITS AFFILIATES (“Aspen”) AND FRANKEL CHEMICALS (“Frankel”) It has come to the attention of Aspen that information allegedly pertaining to the business relationship between Frankel and Aspen has been provided to the international investment community and the general public. Aspen hereby wishes to clarify that the alleged purchases and related amounts owing are invalid and have arisen as a result of the falsification of documents. The allegations are currently sub-judicae. Aspen will co-operate, without restriction, with all statutory investigating authorities and comply with all legal requirements relating to this matter. Frankel have alleged that: (i) “Over the past five years, Frankel Chemicals has been awarded the contract to procure Anti-Retroviral (“ARV”) ingredients for Aspen Pharmaceuticals Ltd in South Africa to combat the spread of HIV/AIDS. The contract was awarded based on the good merits and relations Frankel has with this customer”* (ii) Aspen is indebted to Frankel in the amount of R700 million; (iii) Mr Stephen Saad, the Chief Executive Officer of Aspen, has verbally confirmed “payment terms” with Frankel for the payment of the aforesaid sum of R700 million. Aspen hereby confirms the following facts: (i) Aspen currently purchases selected raw materials directly from Frankel; (ii) Whilst Frankel is listed as an agent of Aspen for the supply of certain other chemicals, Aspen deals directly with the suppliers thereof on a direct indent basis; (iii) Aspen has transacted with Frankel and Frankel International, but has not undertaken business with any of the following entities (which purportedly form part of the Frankel Group), namely: Eurochemicals Pty Ltd Frankel SA Frankel Enterprises Frankel Asset Management Abated Investments; and Bartan Group (Australia). (iv) As at the date of this letter there are no monies due to or owing to Frankel or payable by Aspen to Frankel, or any of its affiliates, for the alleged purchases of ARV materials. (v) Aspen purchases all of its Active Pharmaceutical Ingredients, which are used for the manufacture of ARV products, from other third party suppliers. (vi) Aspen is aware of the existence of documents representing to be purchase orders and other correspondence between Aspen and Frankel which were neither prepared nor authorized by Aspen. These documents have been fraudulently prepared using forged purchase order templates and forged signatures, representing Aspen personnel. Should you have specific queries on this matter, please contact Mr. Pieter van der Sandt, Legal Counsel for Aspen on (011) 239 6522.

Aspen and GSK agree on Strategic Deals

Press Conference Presentation <Click to download> SENS Announcement <Click to download> The Transactions comprise: The acquisition of the rights to distribute GSK products in South Africa by Aspen’s wholly owned subsidiary, Pharmacare Limited (“the SA Component”); The formation of a collaboration arrangement in relation to the marketing and selling of prescription pharmaceutical products in sub-Saharan Africa (“SSA”), (excluding South Africa, Lesotho and Swaziland) between Aspen and GSK, to be known as “GSK Aspen Healthcare for Africa” (“the SSA Collaboration”) The acquisition by a newly formed wholly-owned subsidiary of Aspen of GSK’s manufacturing facility in Bad Oldesloe, Germany as a going concern (“the Facility”); and The acquisition by Aspen’s wholly owned subsidiary, Aspen Global, of eight specialist products for worldwide distribution (“the Products”). Stephen Saad, Aspen Group Chief Executive said: “The Transactions further strategically complement Aspen and GSK’s strong and mutually beneficial relationship which has been fostered over several years. The Transactions will reinforce Aspen’s position as a leading provider of quality, affordable medicines across Africa. The acquisition of additional products for distribution into worldwide markets supports Aspen’s recently implemented internationalisation strategy into emerging markets and the establishment of a global distribution network. ” Aspen two As consideration for the Transactions, Aspen will issue 68.5 million ordinary shares to GSK (approximately 16% of Aspen’s issued ordinary share capital after the issue thereof). On completion of the Transactions GSK will attain the right to nominate one member to the Aspen Board. The final value of the Transactions and the attribution of this value to the individual transactions will depend on the price at which Aspen shares are trading on the JSE upon completion of the Transactions. Details of the Transactions: a) The SA Component: Aspen will acquire the rights to sell, market and distribute GSK’s products in SA for a minimum period of twenty years.GSK will maintain a presence in South Africa through its retained Consumer Healthcare business and the GSK scientific office. b) The SSA Collaboration: GSK and Aspen will enter into a collaboration arrangement for the commercialisation of a portfolio of branded prescription pharmaceutical products in SSA.. The portfolio of products will include a combination of GSK and Aspen products. GSK’s existing distribution platform in SSA will be used for this purpose. Aspen’s subsidiary in East Africa, Shelys, is presently excluded form the ambit of this collaboration arrangement. GSK is one of the leading pharmaceutical companies in SSA, covering most territories in this region with its diverse and recognised portfolio of branded products. Aspen’s extensive product portfolio will supplement GSK’s existing position in the region. The benefits of a combined portfolio of products, supported by a strong distribution network will enable Aspen and GSK to increase access to high-quality, affordable healthcare throughout SSA under the collaboration brand of “GSK Aspen Healthcare for Africa”. c) Acquisition of manufacturing facility in Bad Oldesloe, Germany: Aspen will acquire the business comprising GSK’s manufacturing facility in Bad Oldesloe, Germany as a going concern. The Facility currently manufactures a range of products, including some of the products which Aspen is to acquire from GSK through the Transactions as well as products acquired from GSK through previous transactions. A ten-year supply arrangement with GSK for the continued supply of GSK retained products currently manufactured at the Facility has also been agreed to. The acquisition of the Facility will enhance Aspen’s existing manufacturing base and enable the Group to optimise production capacities to meet demand from its global markets. The technical skills and competence of staff at the Facility will further complement Aspen’s existing manufacturing capability. Aspen three last d) The acquisition of eight specialist products: Aspen Global will acquire eight specialist products from GSK for distribution into worldwide markets, except for Alkeran in the USA which will be retained by GSK. The products are: Alkeran, Leukeran and Purinethol – chemotherapy products which are used in the treatment of cancer; Kemadrin – used to treat and relieve the symptoms of Parkinson’s disease; Lanvis and Myleran – used for the treatment of leukemia; Septrin – a broad-spectrum anti-microbial; and Trandate – used for the treatment of high blood pressure. These products will add to Aspen’s existing global brands portfolio which contains products such as Eltroxin, Lanoxin, Imuran and Zyloric, acquired from GSK in June 2008, as well as Aldomet, Indocid and Aggrastat which are being dristributed under license from Iroko. The completion of the Transactions is subject to the fulfillment of, inter alia, the following conditions precedent: The approval of the Exchange Control Department of the South African Reserve Bank; The consent to the Transactions from Aspen Global’s existing long-term funders; The approval of the relevant competition authorities in relation to the SSA Collaboration; The approval of the SA competition authority in relation to the SA Component; The approval of the relevant competition authorities in relation to the acquisition of Aspen Global for the Products; Approval from the German competition authorities and various other German regulators for the purchase of the Facility; and JSE approval for the listing of the consideration shares. The terms of the agreement are expected to be completed before the end of 2009. From left to right: JUDY DLAMINI (ASPEN CHAIRMAN), STEPHEN SAAD (ASPEN GROUP CHIEF EXECUTIVE), NOEL GULIWE (ASPEN CHIEF EXECUTIVE : SOUTH AFRICA), GUS Issued by: Shauneen Beukes, Shauneen Beukes Communications Tel: (012) 661-8467 : Cell: 082 389 8900 Roshni Gajjar, Aspen Investor Relations Tel: (031) 580-8649 ; Cell: 082 789 1826 On Behalf Of: Stephen Saad, Aspen Holdings Group Chief Executive Tel: (031) 580-8600 Gus Attridge, Aspen Holdings Deputy Group Chief Executive Tel: (031) 580-8600

Aspen’s offshore operations drive an impressive 91% revenue increase

Johannesburg – JSE listed Aspen (Apn), Africa’s largest pharmaceutical manufacturer, has recorded strong revenue growth for the six months ended 31 December 2008. The positive returns were stimulated by Aspen’s recently expanded international operations. The existing businesses in South Africa and Australia have once again recorded sustained growth. Revenue increased by 91 percent to R4 264 million (R2 230 million). Operating profit increased by 84 percent to R1 163 million (R633.8 million). Headline earnings per share (HEPS) increased by 77 percent to 193.8 cents (109.6 cents). Increase in earnings per share (“EPS”) was lower than HEPS at 54 percent to 192.5 cents (125.0 cents) owing to the inclusion of non-recurring capital profits in the determination of EPS in the prior year. Stephen Saad, Aspen Group Chief Executive said “we are pleased to have delivered such positive results in a challenging operating environment. The Group’s international businesses have been the primary growth driver for the period under review. For the first time, profits from offshore operations exceeded those of the South African business. Aspen’s local presence remains strong with increased market share in all pharmaceutical categories. The Group retaining its ranking as the leading pharmaceutical company in the South African private and public market sectors.” SOUTH AFRICAN OPERATIONS Aspen’s South African business increased revenue by 32% to R2 331 million (R1 771 million). This growth was led by the pharmaceutical division which grew sales by 35% to R1 789 million driven by a substantial increase in volumes and a positive performance from recently launched products such as Truvada™, Viread™, Vectoryl™ and Aspen effavirenz. Growth in earnings before interest, tax and amortisation (“EBITA”) was limited to 10% at R586 million owing to a change in product mix due to a lower margin in public sector products, higher commodity prices, inflationary pressures and fixed pricing under both the Single Exit Pricing (“SEP”) regulations and the State Tender awards. The over-the-counter (“OTC”) division delivered good results with leading brands such as Flusin™, Lenadol® and Sinuclear® contributing positively. Aspen has successfully launched replacement products under its major slimming brands Thinz®, Leanor™ and Slenz® due to the South African Medicines Control Council’s (“MCC”) banning of d-norpseudoephedrine, the active ingredient in slimming preparations. Household brands such as Lennon Dutch Medicines®, Woodwards™ Gripewater and Guronsan® C supported the consumer division’s 22% revenue growth which is a pleasing return given the pressure felt in the retail sector. Laxative brands are being re-developed following the MCC’s withdrawal of phenolphthalein-containing products. Excellent returns were recorded by Aspen Nutritionals. The existing portfolio of infant nutritional brands such as Infacare®, S26® and SMA® was enhanced with the launch of Melegi™, which is exported to selected African countries. High levels of productivity were achieved at Aspen’s manufacturing facilities in order to respond to growing volumes. Continued investment in manufacturing will unlock additional capacity at the Port Elizabeth site. Commercialisation of eye-drops at Aspen’s Sterile Facility is expected to take place before year-end. Aspen will supply eye-drops to the USA market under a contract with Prestige Incorporated. INTERNATIONAL OPERATIONS Contributions from Aspen’s international operations increased sharply, following the Group’s recent expansion into more than 100 new markets. An increase in revenue was recorded at R1 934 million (R460 million) while EBITA rose to R630 million (R101 million). The Group also strengthened its intellectual property portfolio with the acquisition of Eltroxin™, Lanoxin™, Imuran™ and Zyloric™ from GlaxoSmithKline (“GSK”) and licensing deals with US-based Iroko Pharmaceuticals for the distribution of products into emerging markets. Revenue from global brands amounted to R696 million. Aspen Australia recorded sustained growth through the expansion of its product offering, thereby increasing revenue by 55% to R484 million (R311.7 million). Group revenue from the Latin American operations comprised 10% with sales of R408 million. The primary contributor was Brazil’s Cellofarm accounting for R330 million, with the Mexican and Venezuelan companies contributing the balance. Strategies are in place to grow the Brazilian market share, with focus being re-directed to the private sector. A brand development strategy has been initiated and 150 experienced sales representatives have been recruited for the fulfilment thereof. Construction of the manufacturing facilities in Campos, Brazil has been completed. The Brazilian authorities have accredited the Penem Facility thereby enabling the commencement of commercial production. The Penicillin Facility is awaiting final regulatory approval. Shelys, the Group’s business in East Africa, recorded revenue of R200 million in Tanzania, Kenya and Uganda. The OTC Manufacturing Facility under construction in Nairobi, is due for completion before the end of 2009. PROSPECTS Growth in South African volumes is expected to remain buoyant during the second half of the year. The 13.2% increase in SEP will offset the impact of higher supply costs. Despite trading difficulties in the retail sector, it is anticipated that the successful strategies implemented by the consumer division will yield favourable results. Additional production capacity will be realised during the forthcoming calendar year when Aspen’s three major capital projects in Port Elizabeth, valued at R1 billion, are completed. The solid dosage manufacturing and packing capabilities will cater for anticipated growth in demand from domestic and international markets. The Sterile Facility will provide Aspen with production capabilities in injectables, hormonal injectables and eye-drops for all major international markets. It is expected that the international businesses will provide significant impetus to the Group’s growth. Cognisance should be taken of influencing factors most notably global currency exposures and world market volatility. The product pipeline for the international business remains a major focus area with benefits expected to become apparent in the next two to three years. The Bangalore Oncology Facility has been accredited by the Australian Therapeutic Goods Association and commercial production is scheduled to commence in 2010. The disposal of Aspen’s 50% shareholding in Astrix remains subject to fulfilment of conditions precedent. Aspen’s performance in the first half of this financial year has shown resilience and strategies have been implemented which are designed to add to the Group’s performance in future years.

Trading Update

Aspen shareholders are hereby advised that earnings per share, for the 6 months ended 31 December 2008, are forecast to exceed those reported in the comparative period ended 31 December 2007, by 45-60%. Headline earnings per share are forecast to exceed those of the comparative period by 65-80%. As anticipated, a strong contribution from Aspen’s recently expanded international operations has been the leading growth driver. The difference between the quantum of the anticipated percentage increase in earnings per share and in headline earnings per share is due to non-recurring capital profits being included in earnings per share in the comparative period. The financial results on which this trading announcement is based have not been reviewed or reported on by Aspen’s external auditors. Aspen’s results are expected to be published on SENS on 05 March 2009. Sponsor Investec Bank Limited

Aspen Appoints Noel Guliwe as Chief Executive in South Africa

JOHANNESBURG: Aspen Holdings is pleased to announce the appointment by its principal South African subsidiary of Noel Guliwe as Chief Executive: South Africa with effect from January 12, 2009. “The rapid globalization of the Aspen Group has necessitated increased attention from Aspen’s senior executives. Consequently, this appointment has been made to ensure that the local business receives ongoing strategic focus and leadership in order that Aspen retains its position as the leading pharmaceutical company in South Africa,” said Stephen Saad, Aspen Group Chief Executive. Noel has vast and credible experience in the pharmaceutical sector which spans nearly 20 years. He joins Aspen following a successful tenure as CEO and country President of Novartis South Africa. His qualifications include a B.Pharm and MBA from the University of the Witwatersrand.

Closed Period

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

The live presentation will take place in Cape Town at 08h30 on 2 March 2023.

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