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APNASPENAspen Pharmacare Hldgs14500-149 (-1.02%)

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

Aspen’s growth formula

On a recent holiday to Disney World with his family, Aspen Pharmacare CE Stephen Saad wandered into a pharmacy while his children enjoyed the rides. On a shelf he found Murine Clear Eyes, the eye drops made at Aspen’s Port Elizabeth plant. “About 2m-3m packs a month are sold around the world but it was good seeing them at Disney World [in the US],” says Saad. “On the box it says ‘made in Port Elizabeth’. I wondered how many customers there knew where Port Elizabeth was; they probably thought it was in England.” The anecdote illustrates the global reach of Aspen, which has enjoyed phenomenal growth in just under two decades, from a converted house in Durban to a multinational group. It is now the largest pharmaceutical company in the southern hemisphere and the ninth-largest generics company in the world . But SA remains the heart of its operations. Products made in SA are exported to the rest of Africa, Australia, China and the US. With a 16% share of the SA pharmaceutical market and 31% share of the generics sector, Aspen is ranked the number one pharmaceutical company in SA by IMS Health, a firm that provides research and other services to the health-care industry. Nearly one in four scripts dispensed by pharmacists in SA is for an Aspen product. After buying Sigma Pharmaceuticals for R5,9bn in 2011, Aspen now has a 4% share of the Australian pharmaceutical market and 16% of its generics sector. In Australia, one in seven scripts is for an Aspen product. In Africa, it is the largest pharmaceuticals firm by sales, market share, presence in different countries, turnover, market capitalisation and production, and the biggest supplier of antiretroviral drugs. However, Saad emphasises that Aspen should not be seen as a group that has grown only through acquisitions. “It’s true that we’ve grown through acquisitions, but more of our growth has been organic.” Aspen is attractive as a rand-hedge investment, because 63% of its operating profit comes from outside SA. Plans are in place to enter new territories and expand further. It supplies branded and generic pharmaceuticals to more than 150 countries, has 23 manufacturing facilities at 17 sites on six continents and employs more than 6000 people . This week its share price was around R266,40, slightly lower than it was at the end of 2013. In the past year the share price has risen by 54,2%. Aspen is one of the more expensive shares on the JSE because the price:earnings multiple is 33,81 times. But the forward p:e is 30,54 times, which means investors expect the company, and share price, to continue doing as well as it has historically. It’s also widely held in institutional investor portfolios. And it has the attractions of consistently high growth in profits, which supports share price growth, as well as steady demand for its products, such as treatments for chronic diseases. Behind this group is a remarkable story of humble beginnings in a house converted into an office, at 94 Fourth Ave in Greyville, a middle-class Durban suburb. The group’s impressive international expansion is based on a formula learnt in the early days: to start small and then grow. “Even now, in new countries for us such as Russia, we move in small, start small, often in rented premises, and grow from there. That’s the way we have done it over and over again.” Saad says much of the group’s success is due to the teams he has working for him in SA and the rest of the world. “There’s a basic value system we drive in the business. We give ownership and trust to our people and let them make lots of the decisions. That’s probably the biggest aspect to Aspen’s success.” That may well be, but a large part of the success comes from Saad and his deputy and long-time colleague, Gus Attridge. Their relationship pre dates Aspen. Saad’s first job in 1989 was at a start-up, Quickmed CC, a small medical wholesale business working mainly in black townships around Durban. It later merged with Zurich, which in 1993 was bought by Prempharm (now Adcock Ingram) for R75m. Saad, at the age of 29, made R20m on the deal. Later that year he teamed up with Attridge and they bought a stake in Varsity College, which was struggling at the time. They turned the educational business around, partly through some innovative marketing in which they offered students their money back if they did not pass, as long as they had attended all their lectures. That was an early example of what was to become the hallmark for Aspen deals. “We identify companies that we know we can run better and make money out of. That’s been the motive behind many of our deals,” Saad says. The stake in Varsity College was sold in 1997 to LeisureNet for R100m. Saad and Attridge had paid R1,5m for it. Two LeisureNet executives were later convicted on fraud charges, but that scandal did not touch Saad and Attridge. Attridge says: “We had some concerns about the two LeisureNet directors we were dealing with. But we monitored it closely and the transaction went through fine.” With the money they made on the Varsity College deal they established and launched Aspen later that year. Both attended the same university, the University of Natal, but met only later. “I was at university earlier than Stephen; I’m older than him. I think we met playing club rugby against each other,” Attridge says. What was then called Aspen Healthcare began trading in 1997 and the following year listed on the JSE through a reverse listing into Medhold. But 1999 proved to be the big year for Aspen, when it bought a major pharmaceutical company, SA Druggists (SAD), for R2,4bn in a hostile takeover. “Without a doubt, in retrospect, SAD was the highest-risk deal we did,” Saad says. “We were confident at the time but if it had gone wrong, we would have lost… Continue reading Aspen’s growth formula

Honouring Former President Nelson Mandela

Johannesburg, Friday 6 December 2013 – Today, as the world mourns the passing of one of its most outstanding citizens and South Africa’s former President, Nelson Rolihlahla Mandela, Aspen, joins the millions of people worldwide, in expressing its deepest condolences to the family and friends of this humble leader. Stephen Saad, Aspen Group Chief Executive said, “Although Madiba’s passing will leave a significant void, his decisive leadership, impeccable values and high moral standing will remain with us and we trust it will continue to inspire nations around the world. Aspen continues to draw inspiration from the leadership example set by Madiba. It is an example we have experienced first hand and which has touched the lives of countless fellow South Africans and others across the globe.” In August 2013, Aspen and the Sifiso Nxasana Paediatric Trust donated R5 million towards the establishment of the Nelson Mandela Children’s Hospital, demonstrating ongoing commitment to Mr Mandela’s vision to ensure that future generations of South Africans receive the healthcare that they rightly deserve. Dr Judy Dlamini, Chairman of the Sifiso Nxasana Paediatric Trust said, “At a personal level, Madiba brought back my human dignity and African pride. He will continue to unite the nation through initiatives that will vastly improve specialist paediatric healthcare in the public sector and provide hope to thousands of children.” Upon the inspired advice of Mandela and others, in April 2001 Aspen sponsored the greenfield establishment of the Engcobo Healthcare Centre, near Madiba’s ancestral home in the Eastern Cape. Engcobo, a primary care facility, was established to reduce the burden on surrounding public facilities and soon became a beacon of hope for many in the area who were provided with access to primary care services. At the inauguration of this clinic, Aspen made a commitment to former President Mandela that it would continue its involvement at Engcobo. Aspen has remained true to this commitment and has provided ongoing support to the Engcobo Clinic for the twelve years since. It is not only the people of Engcobo that continue to benefit from this inspired decision, but indeed many hundreds of thousands more. In the early days of anti-retrovirals (ARV’s), it was the hand of Mandela that once again emerged and as with the clinic, was able to provide hope to the most vulnerable in our society. With ARV treatment prices at $35 000 per patient per year and patents of offshore multinational companies strongly protected, this lifesaving medication seemed clearly out of reach for those who needed it most. Many of these patients received their services at Engcobo, but without ARV’s their lives were at risk. Aspen shared footage of the joint Mandela/Aspen inspired clinic with leading multinational pharmaceutical companies to demonstrate the plight of these people. This proved to be a tipping point to some of these multinational companies who agreed to the granting of licenses on their ARV patents to Aspen and to partner with it in making ARVs more accessible to those who needed it. This enabled Aspen to pioneer the manufacture and distribution of generic ARV’s at some $180 per patient per year, a fraction of the $35 000. These meaningful acts accelerated the introduction of generic ARV’s and saved hundreds of thousands of lives. Madiba’s hand in this was both telling and significant. We thank him and honour him for these acts and many more that he carried out in his life. Since 2011, Aspen has also embraced the Mandela International Day celebrated annually on 16 July – an initiative which lies close to the heart of its people around the world. This year Aspen participated in 36 projects in 14 countries on 6 continents which directly enhanced the lives of some 9 400 beneficiaries. The Group’s commitment to making a meaningful difference to others will continue as we remember the call made by Nelson Mandela who said, “We can change the world and make it a better place. It is in your hands to make a difference”. As we pay our final respects to this remarkable man, the best way to honour him is to follow his examples of decisive leadership, impeccable values and high moral standing. Only then will we have made a difference in the lives of others, particularly those who are the most vulnerable in our society.

Aspen concludes the acquisition of an API Business from MSD

01 October 2013 By : Shauneen Beukes 1 October 2013 Oss, the Netherlands – JSE Limited listed Aspen Holdings, the ninth largest generic pharmaceutical company in the world, has announced that the Aspen Group (“Aspen”), has finalised the acquisition of Active Pharmaceutical Ingredient (API) manufacturing operations and related businesses (“the API Business”) from MSD, known as Merck & Co., Inc. in the US and Canada, with effect from 1 October 2013. This forms part of the larger series of transactions with MSD as announced by Aspen on 18 June 2013 – it was confirmed in this announcement that Aspen would acquire the API Business and had reached agreement for an option to purchase a portfolio of 11 branded finished dosage form molecules (“the Products”) from MSD for a total consideration of R10 billion. Stephen Saad, Aspen Group Chief Executive, said “this deal strongly complements Aspen’s strategic intent of globalising its business by providing access to a niche range of APIs and products. It includes the acquisition of an API facility in Oss that manufactures for MSD and the market generally as well as a satellite facility and sales office in the United States.” In terms of the transaction, Aspen will continue to supply APIs to MSD under a 10-year supply contract, which will provide significant on-going volumes for the API Business. Further opportunities also provide for Aspen to develop finished dosage form products from certain of the APIs such as hormones and peptides.

Aspen acquires GSK brands and manufacturing site for £700 million

Durban, South Africa: Aspen Global Incorporated (“AGI”), a wholly owned subsidiary of Aspen, announced today that it will acquire from GlaxoSmithKline plc (“GSK”) the Arixtra and Fraxiparine/Fraxodi brands (“the Brands”) and business worldwide, except in China, Pakistan and India (“the Excluded Territories”) as well as a specialised sterile production site which manufactures the Brands at Notre Dame de Bondeville, France (“the Site”), collectively (“the Proposed Transaction”) for £700 million in cash, of which £100 million relates to inventory. Stephen Saad, Aspen Group Chief Executive, said: “this deal presents excellent synergistic opportunities for Aspen’s ongoing global expansion strategy. In conjunction with the successful completion of an announced transaction with MSD, the opportunity exists to pursue a more vertically integrated supply chain for heparin based products, leading to benefits such as production / inventory planning and economies of scale in procurement. The Brands to be acquired have strong brand equity and established demand in the markets where they have been promoted and provides Aspen with a market presence in some additional 30 countries.” Arixtra and Fraxiparine/Fraxodi are made at a sterile site and the ability to manufacture steriles is globally recognised as a specialist activity resulting in limited possible competition. This is a factor further underlined by the increased complexity of the manufacturing process of Fraxiparine/Fraxodi due to the biological nature of the active pharmaceutical ingredients (“API”) used in their production. David Redfern, Chief Strategy Officer, GSK, said: “Arixtra® and Fraxiparine® are established products that have consistently delivered strong revenues. However, our focus is on delivering an unprecedented late-stage pipeline and preparing for the launch of approved medicines. Aspen is a long-term partner of GSK and will be able to dedicate the resources that these products deserve to take them forward. Importantly, we are pleased to be able to preserve the vast majority of jobs through this agreement.” Subject to regulatory approvals, it is expected that the majority of commercial operations will transfer to Aspen by the end of the year with the remainder, along with the Site, to follow in the first half of 2014. AGI will also be entering into a put/call option agreement in relation to the rights to the Arixtra and Fraxiparine products in the Excluded Territories, with an option period commencing on 1 January 2018 at a price to be determined at the time of exercise.

Aspen’s revenue soars to R19.3 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), the ninth largest generic company in the world and Africa’s largest pharmaceutical manufacturer, has announced excellent results for the year ended 30 June 2013. Group Performance Revenue from continuing operations increased by 27% to R19.3 billion. Operating profit from continuing operations rose by 28% to R5 billion. Normalised headline earnings, being headline earnings adjusted for specific non-trading items, advanced 32% to R3.8 billion. Normalised diluted headline earnings per share from continuing operations increased by 31% to 836 cents. Total distribution of 157 cents per share comprising a cash dividend of 131 cents per ordinary share and a capital distribution of 26 cents per ordinary share. Stephen Saad, Aspen Group Chief Executive said, “While all business segments recorded substantial growth, the International business excelled with a superb performance driven by a combination of organic and acquisitive revenue growth.. The largest revenue contribution to the Group came from the Asia Pacific business while Latin America was the fastest growing customer geography.” South African Business In the South African business, revenue improved by 20% to R7.4 billion and operating profit before amortisation, adjusted for specific non-trading items (“EBITA”) increased 11% to R2.0 billion. Revenue in the Pharmaceutical division rose 20% to R6.2 billion driven by organic growth and a strong contribution from new product launches in the private sector. In the public sector expanding demand for antiretrovirals (“ARVs”) added to the growth momentum although the greater weighting of revenue from low margin ARVs was the largest factor in the contraction of margin percentages. The weakening of the rand and rising inflation in administered costs also put pressure on margins although this was partially relieved by gains in production efficiency and procurement savings. The Consumer division delivered an 18% increase in revenue with nutritionals being the biggest growth driver. Innovative new products, growing-up-milk and ready-to-feed infant milk were launched expanding Aspen’s offering in the nutritional sector. Capital expansion projects have continued according to plan at all of the South African sites. In Port Elizabeth, land was acquired immediately adjacent to Aspen’s site. Part of this land is already under construction with the commencement of the building of the high containment suite while the remaining land remains available for future projects. The upgrade of packing capabilities is also underway in Port Elizabeth. The expansion and enhancement of manufacturing capabilities is continuing at Fine Chemicals in line with the strategy to achieve greater vertical integration of this site with Group active pharmaceutical ingredient (“API”) demands. The projects underway in East London and at Clayville are nearing completion. Asia Pacific Business The region’s continuous record of growth since the business was established in this territory in 2001 continued with a gain of 26% in revenue to R7.6 billion and with EBITA increasing by 30% to R1.9 billion. Rand-denominated performance was enhanced by the relative strengthening of the local currencies. The Asia Pacific region was the largest contributor to revenue in the Group for the first time, accounting for 37% of total gross revenue. This was achieved despite the mandated price cuts in Australia imposed by existing legislation. Revenue growth was supported by acquired products and pleasing progress in the Asian territories. EBITA advances benefitted from the continuation of the project to source more competitive product costs including the migration of production to the Port Elizabeth site in South Africa. The newly established subsidiary in Malaysia commenced trade in July 2013 and a further subsidiary has been established in Taiwan. Distribution in Australia of the classic brands portfolio acquired by the Group from GlaxoSmithKline (“GSK”) in December 2012 and the infant milk products acquired by the Group from Nestlé in May 2013 have been successfully taken on. International Business The International business showed strong growth with revenue increasing 48% to R3.7 billion and EBITA rising 59% to R1.5 billion. Latin America showed the biggest advance where sales to customers in this territory climbed 53% to R1.6 billion. A combination of organic and acquisitive growth propelled the Latin American performance despite the impact of the currency devaluation in Venezuela. The global brands portfolio was an important contributor to the growth achieved in the International business and the margin improvement projects for these products continued to yield favourable outcomes. Contributions from certain territories in this business have also benefitted from relative currency strength against the rand. Sub-Saharan Africa Business Gross revenue in Sub Saharan Africa increased 26% to R2.1 billion driven by expanded promotional support. The negative growth in EBITA during the first six months was reversed with an increase of 16% in EBITA in the second six months bringing the result for the year to R252 million, an increase of 2%. Impending Transactions Aspen has undertaken extensive corporate activity over the past year and the following transactions are being progression by Group companies: The acquisition of an API manufacturing business, primarily in the Netherlands, from MSD for approximately €36 million plus the value of inventory, to be effective 1 October 2013. Further details appear in the SENS announcement of 27 June 2013. In a related agreement with MSD, Aspen has an option to acquire a portfolio of 11 branded finished dose form molecules covering a diverse range of therapeutic areas for approximately US$600 million. The most likely date for the acquisition of this portfolio through the exercise of the option is 31 December 2013. Further details appear in the SENS announcement of 27 June 2013. A binding, irrevocable offer submitted to GSK to acquire the Arixtra and Fraxiparine/Fraxodi brands worldwide (excluding China, India and Pakistan) together with the specialised sterile production site which manufactures these brands for approximately £700 million. In terms of the offer, the date of acquisition of the brands would be 31 December 2013 and the date of acquisition of the site would be 30 April 2014. Further details appear in the SENS announcements of 18 June 2013 and 24 July 2013. The acquisition of certain licence rights to infant nutritional intellectual property, net assets… Continue reading Aspen’s revenue soars to R19.3 billion

R5 million injection for Nelson Mandela Children’s hospital

Johannesburg: Aspen Pharmacare, a JSE-listed leading pharmaceutical company in the southern hemisphere, provided a financial injection towards the establishment of the Nelson Mandela Children’s Hospital at the inaugural Mandela Sports and Culture Day. Stephen Saad, Aspen Group Chief Executive together with the Minister of Health, Dr Aaron Motsoaledi last year raised R10 million through the Sifiso Nxasana Paediatric Trust for the Children of Africa (“the Trust”), when they cycled the grueling 240km Aspen Trans Karoo race in aid of paediatric healthcare in Africa. Dr Motsoaledi started the race alongside Saad, signaling his support of the need for enhanced access to quality healthcare for all children – irrespective of their socio-economic background. Saad said, “Aspen, together with other donors, is privileged to be able to build on the foundation of quality paediatric healthcare through our R5 million contribution to the Nelson Mandela Children’s Hospital. This demonstrates our commitment to responsible corporate citizenship and we will continue to identify appropriate initiatives aligned to Mr Mandela’s vision and in support of the Department of Health’s programmes to ensure that future generations of South Africans receive the healthcare that they rightly deserve.” “We wish to commend the Minister of Sport, Fikile Mbalula and of Arts and Culture, Paul Mashatile for their vision in conceiving the Mandela Sport and Culture Day. We trust that our contribution on this important day, where the nation honor Madiba, will lead to a further call of action from Corporate South Africa to support this extremely worthwhile initiative,” added Saad. Dr Judy Dlamini, Chairman of the Sifiso Nxasana Paediatric Trust said, “Even from the challenge of a hospital bed, Madiba continues to unite the nation, on this occasion through an initiative that will vastly improve specialist paediatric healthcare in the public sector and provide hope to thousands of children. My family and I would like to extend our sincere gratitude to Stephen Saad’s initiative supported by the National Health Minister, Dr Aaron Motswaledi to assist in the realization of Tat’u Madiba’s wish.” The Trust was established to support the Long Ride for Sifiso Campaign following the untimely passing of Sifiso Nxasana, son of Judy Dlamini and her husband Sizwe Nxasana, CEO FirstRand Ltd.

Aspen signs R10 billion deal with MSD

Oss, Netherlands – JSE Limited listed Aspen Holdings is pleased to announce that the Aspen Group (“Aspen”), the ninth largest generic pharmaceutical company in the world, has: signed an agreement with MSD (known as Merck in the United States and Canada) for the acquisition of an active pharmaceutical ingredient (“API”) manufacturing business which manufactures for MSD and the market generally and which is located in the Netherlands with a satellite facility and sales office in the US (“the API Business”); and reached an agreement on an option to acquire a portfolio of 11 branded finished dose form molecules (“the Products”) from MSD, covering a diverse range of therapeutic areas and including products that use APIs manufactured by the API Business. (collectively “the Transaction”) Stephen Saad, Aspen Group Chief Executive, said “One of Aspen’s primary strategic intents is to further globalise its business, increase its representation across a number of additional territories and provide support to its growing global presence with a differentiated pipeline. This Transaction provides a platform to contribute to the achievement of this strategic intent by enabling Aspen to access a niche range of APIs and finished dosage products.” The Transaction, which is subject to conditions precedent, is valued at approximately US$1 billion (ZAR10.06 billion at ZAR10.06/US$) and comprises the following elements: In respect of the API business: Aspen Holdings will acquire the shares of a new Dutch company (“Dutch Newco”) containing the API Business for a consideration of approximately €36 million (ZAR472 million at ZAR13.11/€); and Dutch Newco will simultaneously acquire inventory with an expected value of approximately €300 million (ZAR3.9 billion at ZAR13.11/€). In respect of the Products: Aspen Global Incorporated, a wholly owned subsidiary of Aspen Holdings, has the option to acquire the Products by way of the exercise of a call option with a resulting asset purchase for a consideration of US$600 million. The effective date of the API Business acquisition is expected to be 1 October 2013 while the expected effective date of the Products acquisition through the exercise of the option is 31 December 2013. Funding: The Transaction, other than certain deferred payments for the MSD inventory and the Products, will be funded from new debt facilities which are at an advanced stage of negotiation. It is planned to fund the deferred payments from Aspen’s existing cash at the time payment is due. The API Business: The API Business consists of manufacturing operations within existing MSD sites comprised as follows: In Oss, the Netherlands, parts of the Moleneind and De Geer sites as well as the entire Boxtel site; and Sioux City, Iowa, in the US. The business also has sales offices at the Oss site in the Netherlands and in Des Plaines, Illinois, in the US. The products manufactured at the sites fall into two categories, namely biochemicals, where biological processes are involved, and chemicals where the process is fully synthetic. The API Business recorded pro-forma revenue of €284 million in the year ended 31 December 2012. The Products: The Products comprise a portfolio of 11 branded finished dosage form molecules, covering a diverse range of therapeutic treatments. The main brands being acquired, by therapeutic area, are: Therapeutic Category Brands Hormone replacement therapy Ovestin, Sustanon, Metrigen Anti-Coagulant Oragan Cortico-Steroid Decadron, Oradexon, Metricorten, Meticortelone Anabolic steroid Deca Durabolin Hyperthyroidism Thyrax, Strumazol Oral Contraceptives Gracial, Novial Vitamin B Complex Benutrex MSD reports that the products which are the subject of the transactions recorded revenue of US$ 248 million in its financial year ended 31 December 2012. More than half of this revenue was generated in Aspen’s key strategic regions of Latin America and Asia Pacific with Europe being the other large territory. The Products will be initially manufactured under the pre-existing MSD manufacturing arrangements in terms of a medium term supply agreement between Aspen Global Incorporated and MSD. Rationale: The following considerations support the rationale for the Transaction: The API Business manufactures heparin, the API used in the manufacture of Fraxiparine, one of the products for which Aspen has made an offer to GSK (refer to Aspen’s cautionary announcement of 18 June 2013); The API Business manufactures the APIs used in a number of the products Aspen will be acquiring under the Transaction, allowing for effective vertical integration; MSD will continue to acquire APIs from Aspen under a 10-year supply contract which will provide significant on-going volumes for the API Business; Aspen plans to improve the cost competitiveness of the APIs; There are opportunities for Aspen to develop finished dosage form products from certain of the APIs such as hormones and peptides; The Products will complement Aspen’s existing portfolio and will provide critical mass to the Aspen offering in a number of markets. This will allow for additional promotional impetus to Aspen’s portfolio of global brands; and These niche Products will substantially supplement Aspen’s growing footprint in a number of emerging and established markets – the notable presence of these products in Latin America and Asia Pacific is supportive of Aspen’s aspirations for these regions.

Renewal of Cautionary Announcement

APN – Aspen Pharmacare Holdings Limited – Trading statement Aspen Pharmacare Holdings Limited (Incorporated in the Republic of South Africa) (Registration number 1985/002935/06) Share code: APN & ISIN: ZAE000066692 (“Aspen”) Renewal of Cautionary Announcement Shareholders are referred to the renewal cautionary announcement released by Aspen on 7 March 2013 in which shareholders were advised of discussions between Aspen and MSD (known as Merck in the United States and Canada) in respect of a possible transaction comprising the acquisition of an active pharmaceutical ingredient facility situated primarily in the Netherlands and a related portfolio of pharmaceutical finished dose form products. These discussions remain ongoing and may have a material effect on the price of Aspen’s securities if successfully concluded and accordingly shareholders are advised to continue exercising caution when dealing in Aspen’s securities. Durban 23 April 2013 Sponsor: Investec Bank Limited

Closed Period

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

The live presentation will take place in Cape Town at 08h30 on 2 March 2023.

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