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APNASPENAspen Pharmacare Hldgs14652152 (1.05%)

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

Press Releases

Aspen cleared of alleged anti-competitive behavior by DA

Durban – JSE Limited-listed Aspen Pharmacare (APN), a leading pharmaceutical company in the southern hemisphere, has welcomed the statement issued by the Democratic Alliance (“DA”) earlier today in which it has confirmed that it is satisfied that there is no evidence that Aspen has engaged in alleged anti-competitive behavior as per the DA’s statement issued on 19 April 2017. The statement issued by the DA on 29 May follows below: Competition Commission investigates conduct of all pharmaceutical companies operating in South Africa and BRICS The DA welcomes the Competition Commission’s preliminary investigation into the market conduct of all pharmaceutical companies operating in South Africa and in the BRICS (Brazil, Russia, Brazil, India, China and South Africa) consortium. The World Bank has raised concerns about cartel-like practices that tend to drive medicine prices upwards and this requires investigation. Following extensive high-level engagements between Aspen Pharmacare and the Health Portfolio of the Democratic Alliance, necessitated by a previous press release, the DA is satisfied that there is no evidence that Aspen is involved in the same practices that they are accused of having pursued in Europe.

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Aspen concludes strategic M.O.U with the Russian Federation

Windhoek, Namibia – JSE Limited listed Aspen Pharmacare (APN), a leading pharmaceutical company in the southern hemisphere, has announced that a memorandum of understanding (“M.O.U”) has been concluded between Aspen’s Russian business and the Vladivostok Far Eastern Federal University (“F.E.F.U”). The Deputy Prime Minister of Russia Mr. Yury Trutnev, who has delegated authority from the Russian President for the Far Eastern Federal Region of Russia, oversaw proceedings and committed the region and university to this collaborative effort. Stavros Nicolaou, Aspen Senior Executive Strategic Trade Development said, “The Group welcomes this latest collaboration with the Russian Federation which further complements existing relations with that country. The M.O.U provides for cooperative efforts to improve the quality of education and contribute towards advanced innovative technology in the fields of thrombosis and anaesthesia through joint training and research efforts with the FEFU. The goal of the programme is to decrease the mortality rate of thrombotic events and to increase the quality of anaesthesia use in the Russian Federation. This will improve the life expectancy of Russian citizens in the medium to long term, as clinicians will have access to some of the newest low molecular weight heparin technology, which has an improved safety profile against older interventions.” Aspen was established in the Russian Federation in 2013 and employs over 150 specialist representatives  detailing critical medicine areas that include anti-thrombosis and anaesthesiology. One of the principle products in Aspen’s thrombosis therapeutic portfolio is Fraxiparine (Nadroparine Calcium), which substantially diminishes the risk of the formation of life-threatening blood clots. This low molecular weight heparin is manufactured through a complex process and provides one of the best in class safety and efficacy anti-thrombotic profiles. Aspen is in discussion with the Ministry of Health for the inclusion of Fraxiparine on the Russian Federation Essential Drug List. The use of anti-thrombotic agents in the Russian Federation is approximately 10% of that of the European Union. In 2015 Aspen commenced technology transfer for the Russian-based manufacture of Fraxiparine through its Russian partner Nanolek L.L.C, which is in the Kirov region of Russia.  Aspen’s products are distributed throughout the Russian Federation.

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Statement in response to The Times of London report on 20 May 2017 on Florinef

Having noted the report published in The Times of London on 20 May 2017 titled “Massive price rise for vital drug put pets’ lives at risk”, Aspen wishes to express its disappointment and concern that much of the information and clarification it provided to The Times’ Billy Kenber prior to the report being published has been excluded. In particular, the Times chose to omit the fact that the product in question, fludrocortisone, is not indicated for use in animals and that the original Aspen product, Florinef, continues to trade actively in the United Kingdom under European Union free trade arrangements. To provide a balanced account of the facts, Aspen wishes to communicate the following information which was shared with the Times, in response to questions: 1. Aspen replaced Florinef with a new product formulation with an improved product stability profile. Florinef is a cold chain product, requiring continuous refrigeration, creating challenges for transportation and storage both in the supply chain and by the patient. The new product is a different formulation which is heat stable and no longer requires such refrigeration. It also removes the risk of discard in case of storage temperature change. The price at which the product was launched in the United Kingdom was considered appropriate considering the cost of developing and launching the new formulation. 2. Pricing approval for the new formulation fludrocortisone was obtained via the NHS BSA prior to launch and the price is registered on the NHS DM&D site. 3. Florinef remains available in the United Kingdom through the free trade arrangements of the European Union and continues to be actively sold in the United Kingdom. 4. Neither Florinef nor the new formulation fludrocortisone are indicated for use as a veterinary product and Aspen can accordingly not take accountability for utilisation of these products by pet owners. We do note that the apparently substantial mark-up by others on the price of the product sold to pet owners contributes to the cost of using this product off-label by pet owners, but must point out that Aspen cannot be deemed to be responsible for this mark-up. 5. As Aspen has the rights to register and supply this improved fludrocortisone tablet formulation globally, there may be scope for cost and price reductions as the product is registered in more countries and the volumes of off-take for it increase. Any further queries in this regard may be directed to Aspen via its website at https://www.aspenpharma.com/contact-form.

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Opening of European Commission proceedings

Aspen confirms that the European Commission has opened proceedings to investigate certain actions of Aspen Holdings and certain of its European subsidiaries. While Aspen is not currently in a position to comment on these proceedings, it reaffirms its commitment to fair and open competition in markets in the European Union and around the world. Aspen takes compliance with competition laws very seriously and will work constructively with the European Commission in its process. Shareholders are advised that any material developments in these proceedings will be communicated through SENS. Shareholders should exercise care when reacting to information on this matter which has not been released by Aspen Holdings.

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Aspen’s response to the reported Competition Commission investigation

Durban – Media reports that the Competition Commission has decided to take up the Democratic Alliance’s request to investigate the alleged anti-competitive conduct of Aspen Pharmacare (“Aspen”) in South Africa, in its preliminary investigation into the pharmaceutical sector, has reference. Aspen welcomes the process and the opportunity to categorically set aside such allegations of anti-competitive behavior.  Aspen is committed to full and constructive engagement with the Competition Commission should it wish to pursue such an investigation. It is worth noting that pharmaceutical prices are approved by the Department of Health in terms of the Single Exit Price regulatory framework which establishes a universal fixed price for each pharmaceutical product.  Aspen has not increased pricing of its products outside of this regulatory framework.

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Statement in response to press reports of 14 and 15 April 2017

In reference to the articles reported in the European press on 14 and 15 April 2017, Aspen Pharmacare Holdings Limited (“Aspen”) has the following comments: Aspen has clearly demonstrated its commitment to providing quality medicines affordably over many years. The supply of the oncology products in question is no exception. Aspen’s status as a responsible and committed provider of quality, affordable medicines is further validated by the role it has played in saving millions of lives across Africa through pioneering and supplying generic anti-retroviral medicine in Africa for the treatment of HIV/AIDS. The content of the reports concern matters that are sub-judice.  Out of respect for the integrity of ongoing legal processes with European regulators, as well as the court in Italy, Aspen will not comment on these public allegations.  Instead, Aspen looks forward to the opportunity to demonstrate the integrity and legality of its practices in the context of these legal processes.    

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Honouring Ahmed M Kathrada

This morning we wake up to the news, that one of the country’s foremost leaders, a true son of the African soil, Ahmed Mohammed Kathrada, Uncle Kathy, had departed our world. Uncle Kathy, as he was and will continue to be affectionately known to us at Aspen, was one of our country’s key architects of the non-racist, non-sexist and equal society that we aspire to today. The “miracle of South Africa” would not have been possible without the selfless toil of the likes of Uncle Kathy. Although our country has lost a great leader, he leaves us with a defining legacy, that we are compelled to continue building on. In recent years Aspen and the Kathrada Foundation have worked closely on a number of projects and initiatives, all aimed at building a better society and in particular improving the plight of the poorest resourced in our society. It is a partnership that we will continue into the future, making a difference to the lives of many South Africans, who need the hope and assistance that the Foundation provides. As we honour this great South African, a humble and modest man, we at the same time pass on our deepest condolences and profound sympathy to our friend and Kathy’s long-time companion, Barbara Hogan, to the Kathrada family and to the Executive Director of the Foundation and his team, Neeshan Balton. May his soul rest in peace and his legacy forever remain a shining example to all.

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Aspen’s half-year revenue increases 13% to R19.8 billion

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), a leading pharmaceutical company in the southern hemisphere, has announced favourable results for the six months ended 31 December 2016. Stephen Saad, Aspen Group Chief Executive said, “The Group has transformed into a global multinational organisation focused on therapeutic specialties over the past few years. This has been a significant undertaking which has required substantial investment in order to build the necessary infrastructure. The contribution from the anaesthesia portfolio acquired from AstraZeneca with effect from 1 September 2016 boosted performance in a period where there were a number of challenges in the operating environment. Particularly pleasing was the marked improvement in cash generated from operating activities which more than doubled as measures to improve working capital management took effect.” GROUP PERFORMANCE • Revenue increased by 13% to R19.8 billion. • Normalised headline earnings per share rose 6% to 692.0 cents. • Normalised EBITDA rose by 7% to R5,5 billion. • Operating cash flow per share escalated 111% to 708,7 cents. • Headline earnings per share increased 53% to 640,9 cents. In addition to the anaesthetics acquisition, the conclusion of a supply and distribution agreement with a major pharmaceutical company which contributed a further R0.4 billion to revenue from the sale of Hydroxyprogesterone Caproate (HPC) in the USA had a positive impact on performance. These upsides were partially offset by the following factors: • The anticipated decline in the South African business which is nonetheless well on its path to recovery; • Margin pressure in the Latin American nutritional business due to reduced production activity as surplus inventories arising from Aspen’s withdrawal from Venezuela were redeployed; • Legislated price decreases, GBP weakness following the Brexit vote, supply constraints and adjustments to the distribution model weighing on performance in the Europe CIS territory; and • Foreign exchange losses, primarily arising from the Rand strengthening against forward exchange contracts. INTERNATIONAL BUSINESS The International business remained the largest segment of the Group, contributing 50% to revenue from customers. Sales to customers in this business increased 11% to R10.0 billion. The Europe CIS territory was the biggest contributor to the International business, increasing sales to customers by 2% to R6.7 billion. Sales of finished dose form pharmaceutical products to healthcare providers (“commercial pharma”) in this territory were up 9% to R4.5 billion. This performance benefitted from the inclusion of the AZ anaesthetics with the offsetting factors mentioned earlier tempering growth achieved. In Latin America, revenue from customers increased 11% to R2.0 billion and commercial pharma sales were 26% higher at R1.3 billion. Excluding the AZ anaesthetics, the underlying pharmaceutical portfolio increased sales 4% to R1.0 billion. Revenue from nutritionals grew in local currencies, but the weakness of the Mexican Peso, in particular, caused reported revenue to decline 9% to R0.7 billion. Margins were unfavorably affected by lower volumes of production in the Vallejo manufacturing site in Mexico for the reasons reported earlier. In the USA, the arrangements with the initially appointed distributor for HPC were terminated and a supply and distribution agreement was signed with a major pharmaceutical company which acquired R0.4 billion of product. Future sales of HPC in the USA will be dependent on the success of this distributor in placing the product in the trade. It is unlikely that there will be further material sales of HPC by Aspen during the 2017 calendar year. Capital projects to enhance production efficiency and ensure highest technical support levels continue at the Notre Dame de Bondeville site in France. At the Oss active pharmaceutical ingredient site in the Netherlands, new capacity is being added and investment in the sustainability of the site is ongoing. SUB-SAHARAN BUSINESS In light of the cancellation of the collaboration with GSK in SSA outside of South Africa, the business segment previously referred to as SSA has been combined with South Africa under the heading of the SSA business. Sales to customers in SSA declined 1% to R4.6 billion. Nutritionals revenue grew 9% to R0.5 billion and manufacturing revenue improved 34% to R0.7 billion. However, as previously communicated, commercial pharma remained under pressure as the resolution of supply chain issues continued, causing sales to decline 8% to R3.4 billion. Despite a month-long strike at the Port Elizabeth and East London manufacturing sites in August, significant progress has been achieved in overcoming the supply constraints affecting the commercial pharma division which delivered improved results in the latter months of the period. The building of a second sterile facility in Port Elizabeth is underway, creating new opportunities to bring additional production to this site. ASIA PACIFIC BUSINESS Sales to customers in the Asia Pacific business increased 36% to R5.2 billion. This region benefits most from the AZ anaesthetics which added R1.6 billion to the sales achieved. In Australasia sales from the base pharmaceutical portfolio grew 3% to R2.3 billion. Sales of nutritionals were 23% lower at R0.4 billion and margin percentages came under pressure. The Australian nutritional industry continues to adapt to lower demand following the withdrawal of informal traders barred from importing product into China. In Asia, the business has expanded substantially with the addition of the AZ anaesthetics. Trade has commenced in China where R0.6 billion of anaesthetic sales was achieved in the period. The underlying commercial pharma portfolio in Asia advanced revenue 17% to R0.9 billion. PROSPECTS In transforming Aspen into a global multinational organisation, it has been necessary to build infrastructure, establish new supply sources and transition management of product portfolios across the world. There have been resultant inefficiencies in overhead structures and working capital management which continue to receive high levels of focus. Unfavourable currency movements and legislated price cuts have also placed pressure on performance. Consequently, this will dilute the synergies realised from various projects. Results in the second half of the 2017 financial year will be influenced by the strengthening of the Rand which, if sustained, will dilute foreign earnings which comprise the greatest portion of Aspen’s income. The outlook to 30 June 2017 will

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Media Enquiries

Shauneen Beukes
Group Communications Consultant
+27 31 580 8600
+27 82 389 8900
sbeukes@aspenpharma.com

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Closed Period

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

The live presentation will take place in Cape Town at 08h30 on 2 March 2023.

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