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APNASPENAspen Pharmacare Hldgs13655106 (0.78%)

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

Minister Ebrahim Patel opens Aspen’s world class general anaesthetic manufacturing line

Stephen Saad, Aspen Group Chief Executive (left) and Honorable Minister of Trade, Industry and Competition, Mr Ebrahim Patel at the unveiling of Aspen's general anaesthetics manufacturing line in Gqeberha, South Africa

Gqeberha, South Africa – Aspen, a global multinational specialty pharmaceutical company, earlier today hosted the Honorable Minister of Trade, Industry and Competition, Mr Ebrahim Patel who officially opened Aspen’s world class general anaesthetics production line at its Gqeberha-based flagship manufacturing site. This manufacturing capability will convert Aspen’s Gqeberha facility into one of the largest manufacturing hubs for general anaesthetic products in the world. The unveiling of the general anaesthetics line follows shortly on the heels of the visit by President Cyril Ramaphosa in March 2021 at the start of the production of the Johnson & Johnson COVID-19 vaccine. Officiating at the opening of Aspen’s general anaesthetics facility, Honorouable Minister Ebrahim Patel said, “This facility consolidates the Eastern Cape as the most significant advanced pharmaceutical hub on the African continent and it will create local jobs. The start of operations is timely as anaesthetics are a class of drug that, among other uses, supports the treatment of COVID-19 patients on ventilators in intensive care units.  South Africa has to date imported the general anaesthetics needed in our healthcare system and the new production line will provide an important medical product for the local market, assuring security of supply, and the bulk of it will be exported across the world, contributing to global patient support.” Stephen Saad, Aspen Group Chief Executive said, “The opening of our general anaesthetics manufacturing line is a significant milestone for Aspen as it will serve as a crucial anaesthetics hub for this critical medication. This is one of the world’s largest general anaesthetics production lines and it positively positions Aspen’s integrated supply, marketing, and sale of anaesthetics globally. Our investment of more than R3.0 billion in this facility is the single largest investment in the pharmaceutical industry in the country and aligns with our commitment to supporting the industrialisation of South Africa.” Sterile Focus Brands, comprising anaesthetic and thrombosis products, is one of Aspen’s key business segments and contributes 28% of revenue. The general anaesthetics production line extends Aspen’s sterile footprint and complements the Group’s strategic vision of delivering quality, affordable medicines using high-technology pharmaceutical equipment, contributing to improved health outcomes for patients.

Aspen increases revenue from continuing operations by 12% to R37,8 billion

Stephen Saad, Aspen Group Chief Executive

Johannesburg – JSE Limited listed Aspen Pharmacare Holdings Limited (APN), a global multinational specialty pharmaceutical company, is pleased to report the following salient financial results for the year ended 30 June 2021: *The prior year comparatives for continuing operations have been restated to include the discontinued European business within discontinued operations in compliance with IFRS 5. The discontinued European business comprises the European Thrombosis assets divested to Mylan until the date of disposal being 27 November 2020, the costs relating to its disposal, related Thrombosis product discontinuations and other product divestments. COMMENTARY GROUP HIGHLIGHTS (CONTINUING OPERATIONS) The commencement of production of COVID-19 vaccines at our Gqeberha manufacturing site in South Africa has been the stand-out achievement in a successful year for Aspen. Johnson & Johnson and Aspen are in discussions to evaluate the further expansion of capacity at the Gqeberha site to enable increased COVID-19 vaccine production, including a possible license for Africa. For the full twelve months, the Group has also continued providing reliable supply of its medicines and products globally despite the ongoing challenges imposed by COVID-19. Group revenue increased 12% to R37,8 billion, with Commercial Pharmaceuticals up 6% and Manufacturing advancing 36%. Normalised EBITDA was 3% higher at R9,9 billion, as a lower gross profit percentage and reduced other operating income were partially offset by well controlled operating expenses. Normalised headline earnings per share (“NHEPS”) increased 10% to R13,10, benefitting from reduced finance costs. Net borrowings declined materially to R16,3 billion as at 30 June 2021, from R35,2 billion in the prior year. The reduction in net borrowings was driven by the cash consideration from the completion of the divestment of the European Thrombosis business, strong operating cash flows and the benefit of a stronger ZAR relative to the EUR and AUD at year-end. The leverage ratio1[1], as at 30 June 2021, is 1,74 times, well below the 3,5 times banking covenant. The table below compares performance from continuing operations in the prior comparable period at reported exchange rates and then at constant exchange rates (“CER”). The difference between reported and CER revenue growth has narrowed since the first half results as a result of the ZAR strengthening during the second half of the current financial year against the majority of the other currencies in which Aspen trades. Continuing operations Reported FY 2021 R’million Restated FY 2020 R’million^ Change at reported rates % Change at CER# % Revenue 37 776 33 659 12 10 Normalised EBITDA* 9 945 9 612 3 1 NHEPS** (cents) 1309,7 1 194,8 10 7 #CER removes the currency effect on performance. FY2020 reported results was recalculated at FY 2021 average exchange rates. This provides illustrative comparability with the current year’s reported performance. ^FY 2020 has been restated as a result of the discontinued operations *Normalised EBITDA represents operating profit before depreciation and amortisation adjusted for specific non-trading items as defined in the Group’s accounting policy ** NHEPS is HEPS adjusted for specific non-trading items, being transaction costs and other acquisition and disposal-related gains or losses, restructuring costs, settlement of product related litigation costs, net monetary adjustments and currency devaluations relating to hyperinflationary economies and significant once-off tax provision charges or credits arising from the resolution of prior year tax matters. DISCONTINUED OPERATIONS Discontinued operations for the year ended 30 June 2021 comprise the results of the European Thrombosis business to date of disposal (being 27 November 2020), the costs relating to its disposal, related Thrombosis product discontinuations, other product divestments and the residual costs related to prior period disposals. Discontinued operations in the prior period include the results of the operations classified as discontinued in the current period as well as those discontinued in the prior financial year. SEGMENTAL PERFORMANCE Commercial Pharmaceuticals Commercial Pharmaceuticals, comprising of Aspen’s Regional Brands and Sterile Focus Brands, grew revenue by 6% (+4% CER) to R27,9 billion. Gross profit increased 4% (+3% CER) to R15,6 billion, supported by a resilient performance from Regional Brands, partially diluted by an unfavourable mix in Sterile Focus Brands as well as higher manufacturing and supply chain costs associated with operating during the pandemic. Regional Brands Regional Brands revenue increased 3% (+2% CER) to R17,2 billion. This is a sound performance given the negative impact from the pricing adjustment to the European oncology products and the persistent unfavourable influence of COVID-19 on certain therapies within this portfolio. A strong performance in OTC products underpinned growth in the key territories of Africa Middle East (+2% CER) and Australasia (+6% CER). Sustained positive revenue gains in Latin America supported the growth in the Americas region (+9% CER). The gross profit percentage improved as cost savings outweighed downsides from the pricing reductions in the oncology portfolio. Sterile Focus Brands Revenue from Sterile Focus Brands increased 11% (+9% CER) to R10,7 billion. Demand remained volatile, following the COVID-19-wave trends with products used as interventions for COVID-19 patients picking up as infections in a country increased while products used in elective surgeries fell. Growth was driven by strong sales in China, Russia and Latin America. Gross profit percentages declined due to changes in product mix. Manufacturing Manufacturing revenue increased 36% (+29% CER). Excluding the supplies to the counterparties of recent transactions, Manufacturing revenue was up 12% (+7% CER). The low/no margin nature of the transaction-related finished dose form supply and the higher costs of production under COVID-19 weighed on the gross profit percentage. COVID-19 vaccine sales (circa R400 million) commenced at the end of the third quarter of the financial year. PROSPECTS The commencement of production of the COVID-19 vaccine at our manufacturing site in Gqeberha towards the end of the third quarter of the financial year ended 30 June 2021 was a landmark event in our endeavours to increase access to medicines, particularly for our home continent of Africa. Our strategy to invest in sterile manufacturing facilities has positioned us to play an increasing role in the provision of the COVID-19 vaccine with potential to make a meaningful contribution to addressing the inequality in access to… Continue reading Aspen increases revenue from continuing operations by 12% to R37,8 billion

Stephen Saad discusses the J&J vaccine release with eNCA’s Sally Burdett

Aspen confirmed on 26 July 2021 that the first supplies to South Africa of the Johnson & Johnson COVID-19 vaccines, from the new API source located in Europe, were being released to Johnson & Johnson from its flagship Gqeberha-based manufacturing site. These vaccines will be further distributed throughout South Africa in line with the various distribution arrangements between Johnson & Johnson, the National Department of Health and other stakeholders. In addition, vaccines from these batches will be made available through the African Vaccine Acquisition Task Team/African Union platform.

Aspen confirms release of Covid-19 vaccines to Johnson & Johnson for supply to South Africa

Durban, South Africa – Aspen, a global multinational specialty pharmaceutical company, is pleased to confirm that the first supplies to South Africa of the Johnson & Johnson COVID-19 vaccines, from the new API source located in Europe, will be released to Johnson & Johnson from its flagship Gqeberha-based manufacturing site later today. These vaccines will be further distributed throughout South Africa in line with the various distribution arrangements between Johnson & Johnson, the National Department of Health and other stakeholders. In addition, vaccines from these batches will be made available through the African Vaccine Acquisition Task Team/African Union platform. This represents a significant landmark for South Africa and the African continent as these are the first COVID-19 vaccines to be produced on the African continent, by an African producer for South African and African patients. Supplies will also be made to the European Union and other offshore markets. Stephen Saad, Aspen Group Chief Executive said, “Aspen is proud of the role we are playing in producing vaccines for distribution in South Africa, across Africa and the world. Our ability to produce these vaccines on behalf of Johnson & Johnson builds on our strategic vision of delivering high quality, affordable medicines that improve health outcomes for patients in our own country, continent and around the world.  Supply for Africa and South Africa is particularly rewarding, given the current global inequality in accessing vaccines. This represents a big step forward in ensuring that Africa can address its healthcare priorities. The manufacture of the Johnson & Johnson COVID-19 vaccine builds on the global contributions we have already made in fighting the COVID-19 pandemic with both our anaesthetics portfolio and dexamethasone supply.” ABOUT ASPEN’S GQEBERHA STERILE SITE Aspen has invested in excess of R3.0 billion at this sterile manufacturing site, based in the Eastern Cape, the single largest investment in the pharmaceutical industry in South Africa. The new sterile facility contains high-technology, state-of-the-art pharmaceutical equipment and systems that will be used to manufacture advanced sterile medicines, including vaccines. These investments at the Gqeberha manufacturing site, which has been a cornerstone of both local antiretroviral and multi drug-resistant TB manufacture, demonstrate Aspen’s ongoing and enduring commitment to South Africa and the continent. With roots firmly embedded in African soil, a continent which carries a disproportionately high disease burden, the investment in advanced pharmaceutical technology enables Aspen to continue to contribute to improved access to treatment, respond to public health emergencies and to create significant economic, export and job creation opportunities. This facility allows Aspen to manufacture multiple and complex sterile products, such as vaccines and Aspen’s global anaesthetics. It will also ensure quality and security of both domestic and international supply. ABOUT ASPEN’S COLLABORATION WITH JOHNSON & JOHNSON It is with much pride and gratitude that Aspen has collaborated with Janssen Pharmaceuticals, Inc. and Janssen Pharmaceutica, NV, two of the Janssen Pharmaceutical Companies of Johnson & Johnson, which have demonstrated their commitment to equitable access to COVID-19 vaccines. Aspen’s Gqeberha site is the only manufacturing site on the African continent and in the southern hemisphere selected by a global multinational pharmaceutical company of this magnitude to contract manufacture COVID-19 vaccines.

CNN Live – Aspen’s US$700m investment in equitable vaccine access for Africa

CNN's Julia Chatterley spoke to Stephen Saad about Aspen's US$700 m investment in vaccine supplies for Africa

“Over 90% of our vaccines are imported. A high majority from #India. When India cut off all exports, #Africa was left without vaccines.” Stephen Saad, CEO @aspenpharma discusses their recent $700M investment & ensuring future Africa supplies.

Aspen statement on manufacture and supply of COVID-19 vaccines

Durban – Aspen, a global multinational specialty pharmaceutical company, was extremely disappointed to learn over the past weekend that specific batches of the Johnson & Johnson COVID-19 vaccine manufactured at our Gqeberha production site and designated for the South African market have to be destroyed due to the Good Manufacturing Practice risk of isolated material in the drug substance supplied to Aspen by Johnson & Johnson from their contract manufacturing partner in the USA, Emergent. The batches manufactured had been retained in storage awaiting the outcome of the US FDA assessment of Emergent.  This is not only a setback to both the Aspen and Johnson & Johnson teams who have worked tirelessly to ensure the manufacture of these batches, but more importantly, has the potential to negatively impact the vaccine rollout across South Africa and Africa. To mitigate the potential risk to vaccine access, and in substitution of the volumes lost, the following actions have been undertaken: We thank the Aspen teams for their exemplary response in managing this setback and our partner, Johnson & Johnson, who through their actions, have not only assisted in capacitating the African continent, but at this challenging time have stepped up again to ensure that we are able to maintain the momentum needed to give our continent access to lifesaving vaccines.

Video: Presentation of Order of Merit to Stephen Saad by President Macron

French National Order of Merit conferred on Aspen’s Stephen Saad

Pretoria – The Chevalier de l’Ordre national du Mérite (Knight of the French National Order of Merit) was bestowed upon Stephen Saad, Aspen’s Group Chief Executive, at the University of Pretoria earlier today.  The national order, originally announced on 11 March 2019, was presented by President Emmanuel Macron at a small event with limited guests in attendance, given heightened Covid-19 gathering protocols.  The National Order of Merit, as awarded by the French President, recognises services and contributions rendered to France, and was created in 1963 by President Charles de Gaulle. Foreigners who have distinguished themselves by their merits in relation to France may be awarded a distinction in the National Order of Merit on the proposal of the Minister of Foreign Affairs and within the limits of specific quotas fixed by decree for a period of three years.  President Macron said, “It gives me great honour to bestow the insigna of Chevalier de l’Ordre national du Mérite upon Stephen Saad, in recognition of his role in developing the economic relations between France and South Africa, as well as his life-long engagement with initiatives that have benefited underprivileged communities across the world.”  Responding to President Macron, Stephen Saad said, “I am deeply humbled and honoured to be recognised with this presentation and I wish to thank President Macron, the French and South African governments for enabling Aspen to contribute towards economic development between our countries. The national order conferred on me is, however, humbly accepted on behalf of Aspen’s employees who have contributed in various roles towards this recognition, most notably our employees in France who take responsibility for the production and commercialisation of our sterile medicines at our manufacturing site in Notre Dame de Bondeville, Normandy. These employees have, despite the many challenges experienced over the last year as a result of the Covid-19 pandemic, remained dedicated to providing healthcare solutions to patients through their expertise, knowledge and passion.”  “Our sterile products produced at the Notre Dame de Bondeville site have, along with a number of other Aspen medicines, played a critical role in treating patients suffering from Covid-19 across Europe and elsewhere in the world. The French government has supported Aspen’s investment and manufacturing initiatives in France since our acquisition of this site in 2013 and we express our sincere thanks to France and its people.” 

Closed Period

Aspen is in a closed period from 1st January 2026 until the publication of the interim results on the JSE SENS platform on the 3rd March 2026.

The live presentation will take place in Cape Town at 08h30 on 2 March 2023.

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